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RECRUITINGINTERVENTIONAL

The Effect of Cord Blood Serum Eyes Drops Administer in Patients With Severe Keratopathy Related to EGFR-I Treatment

Personalized Approach in the Treatment of Patients Affected by Severe Dry Eye Associated With Therapy With EGFR Inhibitors (EGRFR-I) With Growth Factors in Cord Blood Serum (CBS) Eye Drops

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The study aim to evaluate the efficacy of cord blood eye drops in the healing of the damaged corneal epithelium.

Who May Be Eligible (Plain English)

Who May Qualify: - age over 18 years - oncology and advanced cancer patients who have EGFr mutation and who require treatment with antiEGFr drugs - signing of willing to sign a consent form Who Should NOT Join This Trial: - Patients who are unable to store/administer the CSCO independently, or with the help of care-givers. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * age over 18 years * oncology and advanced cancer patients who have EGFr mutation and who require treatment with antiEGFr drugs * signing of informed consent Exclusion Criteria: * Patients who are unable to store/administer the CSCO independently, or with the help of care-givers.

Treatments Being Tested

DRUG

administration cord blood based eye drops, standardized to the deliver BDNF.

administration cord blood based eye drops customized to deliver epitelio tropic factors, incluiding EGF in EGFR blocked cells

Locations (1)

IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Italy