RECRUITINGOBSERVATIONAL
Correlation Between Clinical Neurological Biomarkers and Rehabilitation Outcome
Correlation Study Between Clinical, Neurophysiological, and Neuroradiological Biomarkers and Rehabilitation Outcomes to Predict Functional Recovery After Stroke and Personalize Treatment.
About This Trial
Our study purpose is to evaluate the predictive power of various clinical, neurophysiological, and neuroimaging biomarkers-acquired and analyzed using advanced and integrated techniques-on motor functional recovery and disability post-stroke. The goal is to construct an integrated individual biomarker algorithm with a high predictive value for outcomes.
Who May Be Eligible (Plain English)
Who May Qualify:
- First stroke in the middle cerebral artery territory.
- Ischemic or hemorrhagic stroke (7-30 days post-acute event).
- Upper limb plegia or paresis.
- Both genders, aged \>18 years.
- Ability to provide willing to sign a consent form by the patient or caregiver/responsible relative.
Who Should NOT Join This Trial:
- Previous stroke.
- Stroke in territories other than the middle cerebral artery.
- Inability to provide willing to sign a consent form.
- Contraindications to TMS or MRI.
- History of cancer in the past two years.
- Presence of other neurological conditions interfering with biomarkers
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* First stroke in the middle cerebral artery territory.
* Ischemic or hemorrhagic stroke (7-30 days post-acute event).
* Upper limb plegia or paresis.
* Both genders, aged \>18 years.
* Ability to provide informed consent by the patient or caregiver/responsible relative.
Exclusion Criteria:
* Previous stroke.
* Stroke in territories other than the middle cerebral artery.
* Inability to provide informed consent.
* Contraindications to TMS or MRI.
* History of cancer in the past two years.
* Presence of other neurological conditions interfering with biomarkers
Locations (1)
IRCCS San Raffaele
Roma, Italy, Italy