RECRUITINGPhase 2 / Phase 3INTERVENTIONAL
"The Effect of Inhaled Nitroglycerin for COPD Patients
"The Effect of Inhaled Nitroglycerin on Improving Respiratory Failure in COPD Patients Admitted to Adult Intensive Care Unit"
About This Trial
this study aims to investigative the benefits of using nebulized nitroglycerin in improving respiratory functions in patients of late stage COPD
Who May Be Eligible (Plain English)
Who May Qualify:
- Adult patient's ≥ 18 years old COPD exacerbation with respiratory failure and Echo evidenced presence of pulmonary hypertension (defined as mean pulmonary artery pressure \> 20 mmHg)
Who Should NOT Join This Trial:
- Profound left ventricular failure, as the decrease in pulmonary vascular resistance results in an increase in left ventricular preload. This may worsen cardiogenic pulmonary edema.
- Pregnant female patients
- Patient with hypersensitivity to nitroglycerin
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Adult patient's ≥ 18 years old COPD exacerbation with respiratory failure and Echo evidenced presence of pulmonary hypertension (defined as mean pulmonary artery pressure \> 20 mmHg)
Exclusion Criteria:
* Profound left ventricular failure, as the decrease in pulmonary vascular resistance results in an increase in left ventricular preload. This may worsen cardiogenic pulmonary edema.
* Pregnant female patients
* Patient with hypersensitivity to nitroglycerin
Treatments Being Tested
DRUG
Inhaled nitroglycerin
Inhaled nitroglycerin
Locations (1)
Haram Hospital
Haram, Giza Governorate, Egypt