RECRUITINGINTERVENTIONAL
Hormonal Control of Energy and Macronutrient Intake in Obesity (MEMORY)
Hormonal Control of Energy and Macronutrient Intake in Obesity
About This Trial
The overall aim of the MEMORY study is to examine the concept of 'food memory' - how specific macronutrient compositions influence subsequent food preference and intake, and whether this differs across the BMI range from normal weight to obesity.
Who May Be Eligible (Plain English)
Who May Qualify:
- Age 18-45 years
- For women: Regular menstruation
- BMI-range 18.5-39.9 kg/m\^2
Who Should NOT Join This Trial:
- Not able or willing to eat or drink the test meals because of e.g., allergy or intolerance
- Daily smoking
- For women: Pregnancy / planned pregnancy (within the study period) / lactating
- Self-reported history of an eating disorder
- Self-reported weight change (kg) within two months prior to inclusion
- HbA1c ≥48 mmol/mol
- Treatment with antidepressants
- Alcohol/drug abuse or in treatment with disulfiram (antabus) at time of inclusion
- Uncontrolled medical issues including but not limited to cardiovascular pulmonary, rheumatologic, hematologic, oncologic, infectious, gastrointestinal, or psychiatric disease; diabetes or other endocrine disease; immunosuppression
- Current treatment with medication which significantly affect appetite or energy balance (e.g., GLP-1 receptor agonists)
- Bariatric surgery
- Unable to understand the willing to sign a consent form and the study procedures
- Concomitant participation in intervention studies
- Participant's withdrawal of the willing to sign a consent form
- Other safety concerns - judged by the investigator
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Age 18-45 years
* For women: Regular menstruation
* BMI-range 18.5-39.9 kg/m\^2
Exclusion Criteria:
* Not able or willing to eat or drink the test meals because of e.g., allergy or intolerance
* Daily smoking
* For women: Pregnancy / planned pregnancy (within the study period) / lactating
* Self-reported history of an eating disorder
* Self-reported weight change (kg) within two months prior to inclusion
* HbA1c ≥48 mmol/mol
* Treatment with antidepressants
* Alcohol/drug abuse or in treatment with disulfiram (antabus) at time of inclusion
* Uncontrolled medical issues including but not limited to cardiovascular pulmonary, rheumatologic, hematologic, oncologic, infectious, gastrointestinal, or psychiatric disease; diabetes or other endocrine disease; immunosuppression
* Current treatment with medication which significantly affect appetite or energy balance (e.g., GLP-1 receptor agonists)
* Bariatric surgery
* Unable to understand the informed consent and the study procedures
* Concomitant participation in intervention studies
* Participant's withdrawal of the informed consent
* Other safety concerns - judged by the investigator
Treatments Being Tested
OTHER
High protein liquid test meal
High protein liquid test meal consisting of whey protein, water and sugar-free coadial mix for flavour.
OTHER
High carbohydrate liquid test meal
High carbohydrate liquid test meal consisting of sucrose, water and sugar-free coadial mix for flavour.
Locations (1)
Steno Diabetes Center Copenhagen
Herlev, Denmark, Denmark