RECRUITINGOBSERVATIONAL
The Value of a Convolutional Neural Network-Based Renal Artery Perfusion Model in Predicting Renal Function After Partial Nephrectomy: A Prospective Study
The Value of a Renal Artery Perfusion Model Based on Convolutional Neural Network in Predicting Renal Function After Partial Nephrectomy: A Prospective, Single-Center Study
About This Trial
The goal of this observational study is to develop a CNN-based machine module to predict postoperative fractional renal function in people who are proposed to undergo partial nephrectomy. The main question it aims to answer is: • Does this machine learning model accurately predict renal function after partial nephrectomy?
Who May Be Eligible (Plain English)
Who May Qualify:
- people with stage cT1 renal tumors confirmed by preoperative CT or MR
- people who are proposed to undergoing partial nephrectomy
- localized renal tumors without lymph node and distant metastases as defined by NCCN guidelines
- ECOG score of 0 or 1
- expected to live at least 10 years
Who Should NOT Join This Trial:
- people with surgically unresectable lesions
- people with Abnormal preoperative renal function, eGFR(estimated by CKD-EPI)\<90ml/min/1.73m2
- people who receive preoperative molecular targeted therapy, immunotherapy, chemotherapy
- people with any contraindications to surgery
- people who convert to radical nephrectomy during surgery
- people who receive molecular targeted therapy, immunotherapy or chemotherapy during the postoperative follow-up period
- people with serious systemic disease
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* people with stage cT1 renal tumors confirmed by preoperative CT or MR
* people who are proposed to undergoing partial nephrectomy
* localized renal tumors without lymph node and distant metastases as defined by NCCN guidelines
* ECOG score of 0 or 1
* Life expectancy greater than 10 years
Exclusion Criteria:
* people with surgically unresectable lesions
* people with Abnormal preoperative renal function, eGFR(estimated by CKD-EPI)\<90ml/min/1.73m2
* people who receive preoperative molecular targeted therapy, immunotherapy, chemotherapy
* people with any contraindications to surgery
* people who convert to radical nephrectomy during surgery
* people who receive molecular targeted therapy, immunotherapy or chemotherapy during the postoperative follow-up period
* people with serious systemic disease
Locations (2)
The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital)
Nanjing, Jiangsu, China
The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital)
Nanjing, Jiangsu, China