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RECRUITINGOBSERVATIONAL

Ultrasound-guided Thermal Ablation for Bethesda III/IV Thyroid Nodules

Ultrasound-guided Thermal Ablation for Bethesda III/IV Thyroid Nodules: A Multicenter Study

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

To evaluate the long-term outcomes of ultrasound-guided thermal ablation for Bethesda III/IV thyroid nodules

Who May Be Eligible (Plain English)

Who May Qualify: 1. confirmation of Bethesda III or IV on fine- needle aspiration and negative on Braf V600E test 2. no clinical or imaging evidences of extrathyroidal extension, lymph node metastasis and distant metastasis on ultrasound, neck and chest CT 3. refusal or ineligibility for surgery 4. follow-up time ≥12 months Who Should NOT Join This Trial: 1. follicular neoplasm or malignancy findings on biopsy 2. no suspicious of malignancy in US 3. patients with contra-lateral vocal cord paralysis 4. follow- up time less than 12 months Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: 1. confirmation of Bethesda III or IV on fine- needle aspiration and negative on Braf V600E test 2. no clinical or imaging evidences of extrathyroidal extension, lymph node metastasis and distant metastasis on ultrasound, neck and chest CT 3. refusal or ineligibility for surgery 4. follow-up time ≥12 months Exclusion Criteria: 1. follicular neoplasm or malignancy findings on biopsy 2. no suspicious of malignancy in US 3. patients with contra-lateral vocal cord paralysis 4. follow- up time less than 12 months

Treatments Being Tested

PROCEDURE

ultrasound-guided thermal ablation

microwave ablation, radio frequency ablation, laser ablation

Locations (2)

Chinese PLA General Hospital
Beijing, Beijing Municipality, China
Chinese PLA General Hospital
Beijing, China