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RECRUITINGOBSERVATIONAL

Rituximab and Ocrelizumab in Serum With Multiple Sclerosis

Rituximab and Ocrelizumab in Serum With Multiple Sclerosis (ROS-MS)

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

ROS-MS is a clinical pharmacological substudy to the OVERLORD-MS study (NCT04578639), designed to examine the possibilities of personalized treatment with rituximab and ocrelizumab in patients with relapsing-remitting multiple sclerosis.

Who May Be Eligible (Plain English)

Who May Qualify: - Included in OVERLORD-MS (NCT04578639) - Willing to attend laboratory for blood sample collection at scheduled time points Who Should NOT Join This Trial: \* Not willing to attend laboratory for blood sample collection at scheduled time points Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Included in OVERLORD-MS (NCT04578639) * Willing to attend laboratory for blood sample collection at scheduled time points Exclusion criteria: \* Not willing to attend laboratory for blood sample collection at scheduled time points

Treatments Being Tested

OTHER

Blood samples for PK

Blood sampled for pharmacokinetic study

OTHER

Blood samples for PK

Blood samples before, shortly after infusion of already assigned/ongoing treatment as well as after 2, 4, 8, 12, 24 weeks for serum conc. measurements.

Locations (1)

Haukeland University Hospital, Deparment of medical biochemistry and pharmacology
Bergen, Vestland, Norway