Evaluation of Nasal Biomarkers for Objective Assessment of Disease Severity in Respiratory Disorders

Who May Qualify: - All participants: - 18 years of age or older - The participant must be able to comprehend and sign an approved willing to sign a consent form Form and other applicable study documents. - Healthy volunteers: - No significant sinonasal/pulmonary symptoms or prior diagnoses of sinonasal/pulmonary conditions as determined by pre-enrolment questionnaires. - Case goup: - Participants must be previously diagnosed with rhinitis, chronic sinusitis, asthma, or COPD by a medical professional. Who Should NOT Join This Trial: - Less than 18 years of age at the time of enrolment. - Volunteers who are actively pregnant - Prior history of adverse reaction or contraindicated to diagnostic testing including fingerprick blood sampling, pulmonary testing, nasal swab/sampling. - Any other conditions limiting the volunteer's ability to complete study requirements in the judgement of the investigator/clinician - Any nasal anatomical issue or finding which may limit the safe insertion of the ABEL collection device, as determined by investigator/clinician - History of nasal surgery or trauma within the last 3 months Always talk to your doctor about whether this trial is right for you.