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RECRUITINGINTERVENTIONAL

High vs Low-frequency of High-intensity Training in Chronic Stroke

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The purpose of this pilot study is to investigate the potential role of training frequency on locomotor outcomes following high-intensity gait training and provision of a home walking program.

Who May Be Eligible (Plain English)

Who May Qualify: - Unilateral deficits following stroke \> 6 months prior; however individuals \> 4 months post-stroke are eligible for consenting, but final eligibility and potential enrollment will not occur until \> 6 months - Age 18-85 - Weight \< 350 pounds - Able to follow 3-step commands - Able to ambulate with self-selected gait speeds between 0.10-1.0 m/s without physical assistance, but with below knee bracing and/or assistive device as needed - Lower extremity Fugl-Meyer \< 34 - Medical clearance to participate Who Should NOT Join This Trial: - Evidence of cerebellar ataxia - Uncontrolled cardiopulmonary or metabolic disease that limits exercise participation, active heterotopic ossification, recurrent history of lower extremity fractures, previous orthopedic or other peripheral or central neurologic injury that may impair locomotor activities such that, in the judgement of the PI, could compromise the safety of the participant, limit the ability to complete the study, or compromise the objectives of the study. - Currently participating in other physical therapy - \>50 units of Botox in the lower extremity OR in the lower extremity, but above the knee if the participant wears an ankle-foot-orthosis (AFO) within the past three months Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Unilateral deficits following stroke \> 6 months prior; however individuals \> 4 months post-stroke are eligible for consenting, but final eligibility and potential enrollment will not occur until \> 6 months * Age 18-85 * Weight \< 350 pounds * Able to follow 3-step commands * Able to ambulate with self-selected gait speeds between 0.10-1.0 m/s without physical assistance, but with below knee bracing and/or assistive device as needed * Lower extremity Fugl-Meyer \< 34 * Medical clearance to participate Exclusion Criteria: * Evidence of cerebellar ataxia * Uncontrolled cardiopulmonary or metabolic disease that limits exercise participation, active heterotopic ossification, recurrent history of lower extremity fractures, previous orthopedic or other peripheral or central neurologic injury that may impair locomotor activities such that, in the judgement of the PI, could compromise the safety of the participant, limit the ability to complete the study, or compromise the objectives of the study. * Currently participating in other physical therapy * \>50 units of Botox in the lower extremity OR in the lower extremity, but above the knee if the participant wears an ankle-foot-orthosis (AFO) within the past three months

Treatments Being Tested

OTHER

high-intensity gait training

Individuals will perform up to 40 minutes of walking practice during 60 minute sessions while targeting heart rates of at least 70% heart rate reserve.

BEHAVIORAL

Physical activity coaching

Individuals will receive feedback on the minutes of walking activity performed on non-training days and provided coaching strategies to increase this metric.

Locations (1)

Rehabilitation Hospital of Indiana
Indianapolis, Indiana, United States