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RECRUITINGINTERVENTIONAL

Relationships Between Exercise and Appetite in Women With Loss of Control Eating

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This pilot study is a first step in looking at the relationship between exercise and appetite in women with loss of control eating.

Who May Be Eligible (Plain English)

Who May Qualify: - Engage in loss of control eating at least 12 times in the last three months - Clinically significant eating disorder-related impairment (CIA \> 15) - Taking hormonal contraception - Minimum VO2max of 50th percentile for age and sex assigned at birth - Be willing to eat study-provided foods - Likes chocolate (at least 6/10 on 10 point scale) Who Should NOT Join This Trial: - BMI \< 18.5 kgm/2 - Medical conditions that affect appetite or weight (e.g., diabetes mellitus, thyroid disease) - Recent pregnancy or breastfeeding (prior 6 months) - Relevant food allergies (e.g., wheat, chocolate) - Specific phobia, blood-injection-injury type - Medical condition that precludes safe participation in exercise (e.g., stress fracture) - Medications that acutely affect appetite (e.g., GLP-1 agonists; psychiatric medications allowed) Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Engage in loss of control eating at least 12 times in the last three months * Clinically significant eating disorder-related impairment (CIA \> 15) * Taking hormonal contraception * Minimum VO2max of 50th percentile for age and sex assigned at birth * Be willing to eat study-provided foods * Likes chocolate (at least 6/10 on 10 point scale) Exclusion Criteria: * BMI \< 18.5 kgm/2 * Medical conditions that affect appetite or weight (e.g., diabetes mellitus, thyroid disease) * Recent pregnancy or breastfeeding (prior 6 months) * Relevant food allergies (e.g., wheat, chocolate) * Specific phobia, blood-injection-injury type * Medical condition that precludes safe participation in exercise (e.g., stress fracture) * Medications that acutely affect appetite (e.g., GLP-1 agonists; psychiatric medications allowed)

Treatments Being Tested

BEHAVIORAL

Rest

Participants will eat breakfast but abstain from exercise

BEHAVIORAL

Fed Exercise

Participants will eat breakfast and engage in 30 minutes of physical activity at 75% of their personal V02max.

BEHAVIORAL

Fasted Exercise

Participants will engage in 30 minutes of physical activity at their personal 75% V02max after abstaining from breakfast.

Locations (1)

Ohio University
Athens, Ohio, United States