RECRUITINGINTERVENTIONAL
Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD
Physiologic Effects of Nasal High Flow on Exercise Tolerance in Chronic Obstructive Pulmonary Disease (COPD)
About This Trial
This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L/min) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients and to characterize the association between self-reported dyspnea with and without NHF at 70 L/min following a 6-MWT.
Who May Be Eligible (Plain English)
Who May Qualify:
- Able to consent
- Age 18 years or older
- Diagnosis of COPD
- Ability to ambulate without assistance
- Use of low-flow nasal cannula ≤ 4 L/min or no supplemental oxygen (O2) at all
Who Should NOT Join This Trial:
- Pregnancy
- Being on bedrest
- Inability to consent or cooperate with the study
- Using of \> 4 L/min of supplemental O2 or requiring non-invasive ventilation during the daytime
- Hemodynamic instability (resting heart rate \> 130/minute, systolic blood pressure of ≤ 90 mmHg or ≥ 180 mmHg)
- Metal implants in the thoracic regions (pacemakers, Automatic Implantable Cardioverter Defibrillator (AICD), plates, screws, rods, and disc replacements)
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Able to consent
* Age 18 years or older
* Diagnosis of COPD
* Ability to ambulate without assistance
* Use of low-flow nasal cannula ≤ 4 L/min or no supplemental oxygen (O2) at all
Exclusion Criteria:
* Pregnancy
* Being on bedrest
* Inability to consent or cooperate with the study
* Using of \> 4 L/min of supplemental O2 or requiring non-invasive ventilation during the daytime
* Hemodynamic instability (resting heart rate \> 130/minute, systolic blood pressure of ≤ 90 mmHg or ≥ 180 mmHg)
* Metal implants in the thoracic regions (pacemakers, Automatic Implantable Cardioverter Defibrillator (AICD), plates, screws, rods, and disc replacements)
Treatments Being Tested
DEVICE
Nasal High Flow Cannula
High flow nasal cannula is a device that provides heated and humidified high flow gases. In-person. Depending on participant's availability, up to 6 times
DEVICE
Nasal Low Flow Cannula
Low flow nasal cannula is a device that provides low flow gases. In-person. Depending on participant's availability, up to 6 times
Locations (1)
University of Miami
Miami, Florida, United States