Skip to main content
TrialFinder
TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor about whether a trial is right for you.
RECRUITINGOBSERVATIONAL

Thoracic Fluid Content During Stabilization and Therapeutic De-escalation in Septic Shock

Assessment of Intra-thoracic Water by Bio Reactance During Stabilization and Therapeutic De-escalation in Septic Shock: A Prospective, Multicenter, Observational Study

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

In ICU, fluid challenge represents one of the cornerstones of hemodynamic care. However, fluid overload due to an excessive and/or inappropriate fluid administration could be associated with morbidity or mortality. Unfortunately, there is currently no continuous non-invasive devices to monitor fluid content at bedside. Bio reactance is a non-invasive, rapid and continuous technology developed in order to measure body fluid compartment. Monitoring devices functioning with such technology are promising to evaluate fluid overload in ICU.

Who May Be Eligible (Plain English)

Who May Qualify: - Adult (Age \>18 years old) - Septic shock according to Sepsis-3 definition: - A suspected or confirmed infection - Persisting hypotension, despite adequate fluid resuscitation, requiring vasopressor to maintain a Mean Arterial Pressure (MAP) ≥ 65 mmHg - Lactate level \> 2 mmol/l - Predictive ICU length of stay \> 3 days Who Should NOT Join This Trial: - Admission in ICU for more than 3 days - Refusal to participate - Moribund patients - Decision of therapeutic withdrawal - Curators Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Adult (Age \>18 years old) * Septic shock according to Sepsis-3 definition: * A suspected or confirmed infection * Persisting hypotension, despite adequate fluid resuscitation, requiring vasopressor to maintain a Mean Arterial Pressure (MAP) ≥ 65 mmHg * Lactate level \> 2 mmol/l * Predictive ICU length of stay \> 3 days Exclusion Criteria: * Admission in ICU for more than 3 days * Refusal to participate * Moribund patients * Decision of therapeutic withdrawal * Curators

Locations (2)

Chu Brest
Brest, France
Hegp - Aphp
Paris, France