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RECRUITINGOBSERVATIONAL

OnaBotulinumtoxin-A in Chronic Migraine Patients with Short or Long Disease History (the BACH Study)

OnaBotulinumtoxin-A Effectiveness Evaluation in Chronic Migraine Patients with Short or Long Disease History: an Italian Multicentric Study (the BACH Study)

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The goal of this observational prospective multicentric study, 12 months duration is to investigate whether the history of Chronic Migraine and, more precisely, its duration for over or less than 10 years, can predict OBT-A treatment effectiveness. Since CM patients may have a complex psychopathological profile and psychiatric symptoms represent a bad prognostic factor influencing treatment effectiveness, the present study will also aim at evaluating if the psychopathological profile of the enrolled patients may influence the outcome.

Who May Be Eligible (Plain English)

Who May Qualify: - Age between 18 and 70 years-old - Chronic Migraine defined according to 1.3 ICHD-3 - willing to sign a consent form Who Should NOT Join This Trial: - secondary headache - Onabotulinumtoxin-A in the previous 3 months - pregnancy or breastfeeding - detoxification protocol for Medication Overuse Headache in the last 6 months Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Age between 18 and 70 years-old * Chronic Migraine defined according to 1.3 ICHD-3 * Informed consent Exclusion Criteria: * secondary headache * Onabotulinumtoxin-A in the previous 3 months * pregnancy or breastfeeding * detoxification protocol for Medication Overuse Headache in the last 6 months

Treatments Being Tested

DRUG

OnabotulinumtoxinA OBT-A

Patients will be re-evaluated every 3 months, at each OBT-A cycle, during the whole year of treatment. Every evaluation patients will show their diary of headaches with monthly migraine and headache days and acute medications taken.

Locations (6)

Università Politecnica delle Marche
Ancona, Italy
Università Studi dell'Aquila
L’Aquila, Italy
IRCCS Istituto Auxologico Italiano
Milan, Italy
Istituto Neurologico Besta
Milan, Italy
Fondazione Policlinico Campus Bio-Medico
Roma, Italy
Policlinico Tor Vergata
Roma, Italy