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RECRUITINGOBSERVATIONAL

Identification of Multiple Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled Breath

Exploration and Study on the Identification of Various Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled Breath

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The goal of this observational study is to develop an advanced expiratory algorithm model utilizing exhaled breath volatile organic compound (VOC) marker molecules. This model aims to accurately diagnose mutiple pulmonary diseases. The primary objectives it strives to accomplish are: 1. To assess the diagnostic accuracy of an exhaled breath VOC-assisted diagnostic artificial intelligence (AI) model in diagnose several common pulmonary diseases. 2. To assess the diagnostic accuracy of an exhaled breath VOC-assisted diagnostic artificial intelligence (AI) model in diagnose more pulmonary diseases.

Who May Be Eligible (Plain English)

Who May Qualify: - Males or females, age must be 18 years old or above. - Patients must meet the CT imaging diagnostic criteria for different lung diseases, and patients must be able to provide electronic versions of CT image data. - Patients must have a clear clinical diagnosis. - All participants must sign a written willing to sign a consent form form. Who Should NOT Join This Trial: - Pregnant women. - Individuals with a history of cancer other than lung disease. - Individuals who have undergone organ transplants or non-autologous (allogeneic) bone marrow or stem cell transplants. - Individuals with other severe organic diseases or mental illnesses. - Individuals with metabolic diseases such as diabetes, hyperlipidemia, etc. - Any other condition that researchers deem unsuitable for participation in this clinical trial. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Males or females, age must be 18 years old or above. * Patients must meet the CT imaging diagnostic criteria for different lung diseases, and patients must be able to provide electronic versions of CT image data. * Patients must have a clear clinical diagnosis. * All participants must sign a written informed consent form. Exclusion Criteria: * Pregnant women. * Individuals with a history of cancer other than lung disease. * Individuals who have undergone organ transplants or non-autologous (allogeneic) bone marrow or stem cell transplants. * Individuals with other severe organic diseases or mental illnesses. * Individuals with metabolic diseases such as diabetes, hyperlipidemia, etc. * Any other condition that researchers deem unsuitable for participation in this clinical trial.

Treatments Being Tested

OTHER

Gas chromatography-mass spectrometry(GC-MS) and micro Gas Chromatography-photoionisation detector (μGC-PID) system

Exhaled breath samples from these participants will be collected and analyzed to detect volatile organic compound molecules in human exhaled breath by GC-MS and μGC-PID

Locations (1)

The First Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China