RECRUITINGINTERVENTIONAL
Trabeculopuncture as Predictive Test for the Success of Ab Interno Trabeculectomy
Determining Distal Outflow Tract Function in Open Angle Glaucoma as a Predictive Test for the Success of Ab Interno Trabeculectomy
About This Trial
The purpose of this study is to perform trabeculopuncture a test to determine the distal outflow tract function to predict the success of ab interno trabeculectomy.
Who May Be Eligible (Plain English)
Who May Qualify:
- individuals ≥ 18 years of age
- clinical diagnosis of: primary open angle glaucoma, pigmentary glaucoma, or pseudoexfoliation glaucoma
- uncontrolled intraocular pressure (IOP) with maximally tolerated medical therapy
- progressive thinning of retinal nerve fiber layer assessed by Spectral domain optical coherence tomography (p \< 0.05)
- progression of visual field defects
- visually significant cataract and indication to reduce IOP or glaucoma medication burden
Who Should NOT Join This Trial:
- clinical diagnosis of neovascular glaucoma, angle-closure glaucoma, uveitic glaucoma, neovascular glaucoma
- prior glaucoma surgery
- preexisting conditions affecting the episcleral venous pressure including Grave's ophthalmopathy, Sturge-Weber syndrome, Arteriovenous fistulas (carotid-cavernous fistula)
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* individuals ≥ 18 years of age
* clinical diagnosis of: primary open angle glaucoma, pigmentary glaucoma, or pseudoexfoliation glaucoma
* uncontrolled intraocular pressure (IOP) with maximally tolerated medical therapy
* progressive thinning of retinal nerve fiber layer assessed by Spectral domain optical coherence tomography (p \< 0.05)
* progression of visual field defects
* visually significant cataract and indication to reduce IOP or glaucoma medication burden
Exclusion Criteria:
* clinical diagnosis of neovascular glaucoma, angle-closure glaucoma, uveitic glaucoma, neovascular glaucoma
* prior glaucoma surgery
* preexisting conditions affecting the episcleral venous pressure including Grave's ophthalmopathy, Sturge-Weber syndrome, Arteriovenous fistulas (carotid-cavernous fistula)
Treatments Being Tested
DIAGNOSTIC_TEST
Trabeculopuncture
Trabeculopuncture is performed with a Nd:YAG laser on the trabecular meshwork. Four punctures are created along the 180° nasal trabecular meshwork.
Locations (1)
Uniklinikum Würzburg
Würzburg, Bavaria, Germany