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RECRUITINGPhase 2 / Phase 3INTERVENTIONAL

Long-Term Safety and Efficacy of HB0034 in Subjects With Generalized Pustular Psoriasis

A Phase IIb, Long-Term Extension Study to Evaluate the Safety and Efficacy of HB0034 in the Treatment of Adult Subjects With Generalized Pustular Psoriasis

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This is a Phase IIb, long term extension study to evaluate the safety and efficacy of HB0034 in adult subjects with generalized pustular psoriasis (GPP).

Who May Be Eligible (Plain English)

Who May Qualify: - Patients participated in the preceding placebo-controlled Phase 2 study (HB0034-04)and completed at least the Week 12 visit of the HB0034-04 study - Subject must be a candidate for prolonged GPP treatment according to the Investigator's judgment - Men and women of reproductive age who have no parenting plans and are willing to use reliable contraception during the study period and for 6 months after the last dose of the study drug; - Patients who fully understand and voluntarily sign an ICF, and are willing and able to follow clinical study and subsequent visit schedules Who Should NOT Join This Trial: - Patients who are experiencing GPP flare Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Patients participated in the preceding placebo-controlled Phase 2 study (HB0034-04)and completed at least the Week 12 visit of the HB0034-04 study * Subject must be a candidate for prolonged GPP treatment according to the Investigator's judgment * Men and women of reproductive age who have no parenting plans and are willing to use reliable contraception during the study period and for 6 months after the last dose of the study drug; * Patients who fully understand and voluntarily sign an ICF, and are willing and able to follow clinical study and subsequent visit schedules Exclusion Criteria: * Patients who are experiencing GPP flare

Treatments Being Tested

DRUG

HB0034

300mg, i.v. Q4W

Locations (3)

Peking University People's Hospital (PKUPH)
Beijing, China
Peking University People's Hospital
Beijing, China
The Second affiliated Hospital zhejiang University School of Medicine
Hangzhou, China