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RECRUITINGINTERVENTIONAL

Atlantic Lipid Lowering Treatment Optimization Program

Atlantic Lipid Lowering Treatment Optimization Program (ALLTOP): A Comprehensive Approach to the Treatment of Familial Hypercholesterolemia and Complex Dyslipidemias

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Hypercholesterolemia is recognized as the major driver for cardiovascular morbidity and mortality. To help address this in our community, Atlantic Medical Group (AMG) formed a lipid workgroup chaired by Robert D. Fishberg, MD, and Jeffrey N. Feldman, MD. The overarching goal of the lipid workgroup is to enhance the treatment of lipid disorders in those patients with abnormal lipid levels by improving access to resources at the primary care practice level and specialty level. We aim to develop a model for primary and secondary prevention that integrates guidelines for treatment at the practice level. Our primary objective is to identify high-risk patients by utilizing the electronic health record and partnering with patients' primary care providers to provide comprehensive medical management.

Who May Be Eligible (Plain English)

Who May Qualify: - LDL-C ≥160 mg/dL - Untreated LDL-C ≥190 with family history of CAD - Prior MI and currently without optimized lipid-lowering therapy - Family history of CAD in first degree relative - Personal history of CAD - Untreated triglycerides \>500 - Elevated Lp(a) and/or high calcium scores - Consenting individuals Who Should NOT Join This Trial: - Individuals who are pregnant - Individuals who are incarcerated - Individuals with a terminal illness - Individuals who do not consent Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * LDL-C ≥160 mg/dL * Untreated LDL-C ≥190 with family history of CAD * Prior MI and currently without optimized lipid-lowering therapy * Family history of CAD in first degree relative * Personal history of CAD * Untreated triglycerides \>500 * Elevated Lp(a) and/or high calcium scores * Consenting individuals Exclusion Criteria: * Individuals who are pregnant * Individuals who are incarcerated * Individuals with a terminal illness * Individuals who do not consent

Treatments Being Tested

OTHER

Supportive care

The study model will utilize the accepted standard of care while implementing key enhancements to proactively reach high-risk patients as early as possible. Wrap around comprehensive care is defined as database screening, outreach, encouraging genetic testing for participants and their family members, and provide ongoing education, medical management (e.g., adherence to FDA-approved medications), routine laboratory testing, specialist referrals, Epic referrals to integrated care support such as pharmacy, nutrition, social work, and community health), and routine follow-up either in-person or using virtual visits. Consultations with pharmacists, nutritionists and genetic counselors or specialists to manage co-morbidities may be requested.

Locations (2)

Atlantic Medical Group
Clark, New Jersey, United States
Atlantic Medical Group
Springfield, New Jersey, United States