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RECRUITINGINTERVENTIONAL

RAPID-POP a Randomized Controlled Trial

Efficacy of the Pressure Optimization Protocol (POP )Versus Conventional Stent Deployment Strategy During Primary Percutaneous Coronary Intervention.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Efficacy of the Pressure Optimization Protocol (POP) versus Conventional Stent Deployment Strategy during Primary PCI: An Open Label Randomized Clinical Trial The investigators will compare conventional rapid stent inflation/deflation during primary PCI with higher pressure and prolonged duration of stent deployment Study Hypothesis: The POP in stent deployment is superior to the conventional stent deployment approach with a significantly higher achievement of the TIMI III flow, significantly lesser occurrence of slow flow/no-reflow, and significantly higher rate of ST-Segment resolution during primary PCI.

Who May Be Eligible (Plain English)

Who May Qualify: - Patients aged 18 years and above. - Patients undergoing primary percutaneous coronary intervention (PCI) with stent implantation. - Presence of significant coronary artery stenosis (greater than 70% diameter reduction) confirmed by angiography. Who Should NOT Join This Trial: - Patients with Killip class IV - Patients with significant comorbidities such as end-stage renal disease or advanced liver disease which may interfere with the procedure or follow-up. - Prior history of coronary artery bypass grafting (CABG). - Refusal to give consent for study participation or procedure Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Patients aged 18 years and above. * Patients undergoing primary percutaneous coronary intervention (PCI) with stent implantation. * Presence of significant coronary artery stenosis (greater than 70% diameter reduction) confirmed by angiography. Exclusion Criteria: * Patients with Killip class IV * Patients with significant comorbidities such as end-stage renal disease or advanced liver disease which may interfere with the procedure or follow-up. * Prior history of coronary artery bypass grafting (CABG). * Refusal to give consent for study participation or procedure

Treatments Being Tested

PROCEDURE

Primary Percutaneous Coronary Intervention (PPCI)

Patients presented with acute myocardial infarction undergoing primary percutaneous coronary intervention with stent deployment

Locations (1)

National institute of cardiovascular diseases
Karachi, Sindh, Pakistan