A Registry Based Randomized-Controlled Trial of an Upper Limb Exergaming Intervention for Children and Adolescents With Spinal Muscular Atrophy

Who May Qualify: - Confirmed genetic diagnosis of 5q SMA - Age at screening: Aged 8-18 years old - Participant is able to stay seated independently without support for at least 10 seconds - Participants has a score of at least 2 points in entry item A of the RULM (i.e., "Can raise 1 or 2 hands to the mouth but cannot raise a 200 g weight in it to the mouth") - Treated with disease-modifying therapy - Signed ICF Who Should NOT Join This Trial: - Inability to comply with study procedures according to the site investigator, prior to randomization - Severe scoliosis or contractures that would interfere with gameplay or with successful completion of functional assessments, as confirmed by the clinical evaluator - Planned orthopedic surgery 6 months prior to or throughout intervention and follow-up period (16 weeks post randomization) - Inability to read in English or French Always talk to your doctor about whether this trial is right for you.