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RECRUITINGOBSERVATIONAL

Study of the Prevalence of Autistic Traits in Angelman Syndrome

Study of the Prevalence of Autistic Traits in Angelman Syndrome, the Correlation With Cognitive Level, Epilepsy, With Socio-communication Skills and Parenting Styles

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The goal of this observational cross-sectional study is to establish the prevalence of autism spectrum disorder in children and adolescents with Angelman syndrome. The main questions it aims to answer are: * which clinical variables differentiate AS patients with and without Autism Spectrum Disorder between genetics, epilepsy, pharmacotherapy, behavioural problems, parenting style and parents' perceived stress. * which clinical variables differentiate parenting styles and levels of perceived stress. Data from neuropsychological, speech therapy and physiotherapeutic assessments are collected during regular clinical follow-ups, regarding: cognitive development ("Bayely Scales of Infant Development-III", Cognitive Scale) and adaptive behaviour; Autism and Autism Spectrum Disorder ("Autism Diagnostic Observational Schedule-2"); parental stress and parenting styles; social-communicative skills; motor development.

Who May Be Eligible (Plain English)

Who May Qualify: - genetically confirmed diagnosis of Angelman Syndrome - chronological age between 4-15 years Who Should NOT Join This Trial: - genetic examination pending report - mental age lower than 12 months - brain injury acquired in the peri- or postnatal period Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * genetically confirmed diagnosis of Angelman Syndrome * chronological age between 4-15 years Exclusion Criteria: * genetic examination pending report * mental age lower than 12 months * brain injury acquired in the peri- or postnatal period

Locations (1)

I.R.C.C.S. "E.Medea"
Conegliano, Treviso, Italy