Efficacy and Safety Study of 610 in Patients With Severe Asthma

Who May Qualify: 1. Able to give written willing to sign a consent form prior to participation in the study. 2. Male or female adults ages 18 to 75 years old when signing the willing to sign a consent form. 3. Documented diagnosis of asthma for at least one year prior to screening. 4. History of physician-diagnosed asthma requiring treatment with ICS and at least one other control medication for at least 6 months prior to screening. Who Should NOT Join This Trial: 1. Presence of a known pre-existing, clinically important lung condition other than asthma. 2. Severe asthma exacerbation within 4 weeks prior to randomization. 3. Subjects with any eosinophilic diseases other than asthma. 4. Known, pre-existing severe or clinically significant cardiovascular disease. 5. known, pre-existing other concurrent clinically significant medical conditions that are uncontrolled with standard treatment. 6. Subjects who have active Hepatitis B, Hepatitis C or HIV infections as determined by positive results at Screening. 7. Subjects with allergy/intolerance to a monoclonal antibody. Always talk to your doctor about whether this trial is right for you.