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RECRUITINGINTERVENTIONAL

The Adherence of Proactive Sleep Apnea Therapy

Evaluating and Comparing the Adherence of Proactive Management Therapy for Sleep Apnea

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The goal of this clinical trial is to compare the adherence to Positive Airway Pressure (PAP) therapy for newly diagnosed Obstructive Sleep Apnea (OSA) patients. The main question(s) it aims to answer are: 1. To compare the adherence of proactive therapy and conventional Automatic-PAP (APAP) therapy short-term (3 months) and long-term (12 months) for newly diagnosed OSA patients. 2. To compare health outcomes (AHI, nightly usage, leak, and patient-reported outcomes) between proactive therapy and conventional APAP therapy.

Who May Be Eligible (Plain English)

Who May Qualify: - Must have a new diagnosis of moderate or severe OSA (i.e., AHI \> 15 events/hour). - Must be 18-70 years old. - No history of self-reported, uncontrolled, severe cardiovascular or neurological issues. - Must be able to comply with all study requirements as outlined in the consent form. - Must be able to follow the directions of the study doctor and research team. - Must be able to understand English and be willing to provide willing to sign a consent form. Who Should NOT Join This Trial: - Prior use of PAP machines. - Subjects actively using bi-level PAP or require oxygen therapy. - Subjects who are medically complicated or who are medically unstable ( i.e., cancer, dementia, unstable cardiac or respiratory disease, or unstable psychiatric illness). - Potential sleep apnea complications that, in the opinion of the clinician, may affect the health and safety of the participant. - Inability or unwillingness to given written willing to sign a consent form. - Neuromuscular disease, hypoglossal-nerve palsy, severe restrictive or obstructive pulmonary disease, moderate-to-severe pulmonary arterial hypertension, severe valvular heart disease, New York Heart Association class III or IV heart failure, recent myocardial infarction or severe cardiac arrhythmias (within the past 6 months), persistent uncontrolled hypertension despite medication use, active psychiatric disease, and coexisting non-respiratory sleep disorders that would confound functional sleep assessment. - Pregnancy, planning to attempt to become pregnant, or breastfeeding. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Must have a new diagnosis of moderate or severe OSA (i.e., AHI \> 15 events/hour). * Must be 18-70 years old. * No history of self-reported, uncontrolled, severe cardiovascular or neurological issues. * Must be able to comply with all study requirements as outlined in the consent form. * Must be able to follow the directions of the study doctor and research team. * Must be able to understand English and be willing to provide informed consent. Exclusion Criteria: * Prior use of PAP machines. * Subjects actively using bi-level PAP or require oxygen therapy. * Subjects who are medically complicated or who are medically unstable ( i.e., cancer, dementia, unstable cardiac or respiratory disease, or unstable psychiatric illness). * Potential sleep apnea complications that, in the opinion of the clinician, may affect the health and safety of the participant. * Inability or unwillingness to given written informed consent. * Neuromuscular disease, hypoglossal-nerve palsy, severe restrictive or obstructive pulmonary disease, moderate-to-severe pulmonary arterial hypertension, severe valvular heart disease, New York Heart Association class III or IV heart failure, recent myocardial infarction or severe cardiac arrhythmias (within the past 6 months), persistent uncontrolled hypertension despite medication use, active psychiatric disease, and coexisting non-respiratory sleep disorders that would confound functional sleep assessment. * Pregnancy, planning to attempt to become pregnant, or breastfeeding.

Treatments Being Tested

DEVICE

Proactive CPAP Therapy

CPAP machine uses Artificial Intelligence to make predictions and preventions of future apneic events to auto-adjust pressure.

DEVICE

Conventional APAP Therapy

CPAP machine relies on the detection of respiratory events to determine how to react and auto-adjust pressure.

Locations (1)

NovaResp Technologies Inc.
Halifax, Nova Scotia, Canada