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RECRUITINGINTERVENTIONAL

ASHA Bangladesh--An Integrated Intervention to Address Poverty and Depression

ASHA Bangladesh--An Integrated Intervention to Address Depression in Low Income Rural Women

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The goal of this randomized controlled trial is to compare the impact of an integrated intervention combining poverty alleviation and depression treatment to depression treatment alone, in low income rural Bangladeshi women with depression. The main question\[s\] it aims to answer are whether adding poverty alleviation to depression treatment in an integrated intervention: 1) improves depression outcomes at 6 months post baseline as measured by changes in the PHQ-9 from baseline--compared to depression treatment alone; 2) reduces the chance of relapse (PHQ-9 \>=5) at 18 months among patients who remitted (PHQ-9\<5) at six months--compared to depression treatment alone; and 2) whether adding poverty alleviation to depression treatment improves implementation outcomes including treatment uptake and retention--compared to depression treatment alone. Other outcomes that will be studied include economic vulnerability and psychosocial variables such as anxiety, culturally specific symptoms, quality of life, and function. Participants in both arms will participate in research interviews at 6,12 and 18 months. The project also includes a mixed methods implementation evaluation. Quantitative implementation outcomes to be examined include adoption/uptake; retention in the intervention, and fidelity of intervention delivery. A qualitative process evaluation will include interviews with 80 study participants and approximately 40 staff members, including research staff, agricultural officers, and interventionist staff.

Who May Be Eligible (Plain English)

Who May Qualify: 1. Age 18-45 2. Meets criteria for Economic Vulnerability as measured by: household income \<= 15000 Taka per month; food insufficiency in household over previous six months; OR owning \<= 10 decimals of land 3. Family willingness to participate in the program 4. Basic literacy as measured by ability to read a simple sentence; 5. A score \>=10 on the Patient Health Questionnaire (PHQ-9 Depression Scale) at baseline Who Should NOT Join This Trial: 1. Pregnancy at screen; 2. Cognitive or physical impairment precluding participation 3. Plans to relocate or to travel for \> 1 month during 18 M period. 4. Household debt greater than 70,000 Taka Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: 1. Age 18-45 2. Meets criteria for Economic Vulnerability as measured by: household income \<= 15000 Taka per month; food insufficiency in household over previous six months; OR owning \<= 10 decimals of land 3. Family willingness to participate in the program 4. Basic literacy as measured by ability to read a simple sentence; 5. A score \>=10 on the Patient Health Questionnaire (PHQ-9 Depression Scale) at baseline Exclusion Criteria: 1. Pregnancy at screen; 2. Cognitive or physical impairment precluding participation 3. Plans to relocate or to travel for \> 1 month during 18 M period. 4. Household debt greater than 70,000 Taka

Treatments Being Tested

BEHAVIORAL

Manualized Group Based Psychotherapy

Participants in the control group will receive a 10-session 6-month manualized group based psychotherapy treatment. The treatment is adapted from a WHO program called Problem Management Plus (PM+). PM+ includes 4 evidence based strategies: 1) problem solving; 2) increasing social support; 3) behavioral activation; and 4) relaxation through deep breathing. The intervention is delivered by trained non professional peers.

OTHER

Poverty Alleviation

In addition to the psychotherapy intervention described above, participants in the experimental group will receive a poverty alleviation intervention adapted from the well-known Graduation Program--a poverty alleviation intervention widely used in low income countries. The poverty alleviation intervention includes a) 4 sessions of financial literacy education; b) savings accounts; c) consumption support equal to the cost of 1kg of rice per day for six months; d) productive asset transfer of 3 goats; e) 12 months of animal feed and veterinary care; f) gardening supplies; g) agricultural skill building.

Locations (1)

International Centre for Diarrhoeal Disease Research
Dhaka, Dhaka Division, Bangladesh