RECRUITINGOBSERVATIONAL
A Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) Treated With T-cell Redirectors Outside of Clinical Trials
A Retrospective, Multicountry Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma Treated With T-cell Redirectors Outside of Clinical Trials
About This Trial
The purpose of this study is to describe the use of teclistamab/talquetamab in the treatment of patients with RRMM outside of clinical trials.
Who May Be Eligible (Plain English)
Who May Qualify:
- Have a documented diagnosis of multiple myeloma
- Received the first dose of teclistamab on or before 31 December 2022, regardless of the duration of teclistamab treatment (REALiTEC cohort 1) OR Received the first dose of teclistamab from 01 January 2023 to 31 December 2024, inclusive, regardless of the duration of teclistamab treatment (REALiTEC cohort 2) OR Received the first dose of teclistamab from 01 January 2025 to 31 December 2025, inclusive, regardless of the duration of teclistamab treatment (REALiTEC cohort 3) OR Received the first dose of talquetamab on or before 31 December 2023, regardless of the duration of talquetamab treatment (REALiTAL cohort). Participants who received both teclistamab \& talquetamab can be included in both REALiTEC and REALiTAL cohorts
- Received at least one dose of teclistamab/talquetamab
- Provision of a patient-signed willing to sign a consent form form (ICF), or an ICF waiver for deceased patients as applicable based on country/site-specific requirements
Who Should NOT Join This Trial:
- To be excluded from REALiTEC cohorts if received teclistamab as part of an interventional clinical trial
- To be excluded from REALiTAL cohort if received talquetamab as part of an interventional clinical trial
- Participants who have received teclistamab as part of a Janssen pre-approval access program are excluded from the REALiTEC Cohort 2 and REALiTEC Cohort 3
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Have a documented diagnosis of multiple myeloma
* Received the first dose of teclistamab on or before 31 December 2022, regardless of the duration of teclistamab treatment (REALiTEC cohort 1) OR Received the first dose of teclistamab from 01 January 2023 to 31 December 2024, inclusive, regardless of the duration of teclistamab treatment (REALiTEC cohort 2) OR Received the first dose of teclistamab from 01 January 2025 to 31 December 2025, inclusive, regardless of the duration of teclistamab treatment (REALiTEC cohort 3) OR Received the first dose of talquetamab on or before 31 December 2023, regardless of the duration of talquetamab treatment (REALiTAL cohort). Participants who received both teclistamab \& talquetamab can be included in both REALiTEC and REALiTAL cohorts
* Received at least one dose of teclistamab/talquetamab
* Provision of a patient-signed informed consent form (ICF), or an ICF waiver for deceased patients as applicable based on country/site-specific requirements
Exclusion Criteria:
* To be excluded from REALiTEC cohorts if received teclistamab as part of an interventional clinical trial
* To be excluded from REALiTAL cohort if received talquetamab as part of an interventional clinical trial
* Participants who have received teclistamab as part of a Janssen pre-approval access program are excluded from the REALiTEC Cohort 2 and REALiTEC Cohort 3
Treatments Being Tested
OTHER
Teclistamab
No Intervention will be administered during the study. Retrospective data analysis using participants medical records collected within this study will be entered into CRF.
OTHER
Talquetamab
No Intervention will be administered during the study. Retrospective data analysis using participants medical records collected within this study will be entered into CRF.
Locations (20)
Aalborg Sygehus Syd
Aalborg, Denmark
Aarhus Universitetshospital
Aarhus N, Denmark
Rigshospitalet
Copenhagen, Denmark
Odense University Hospital
Odense, Denmark
Sygehus Lillebælt, Vejle
Vejle, Denmark
Hopital Albert Calmette - CHU Lille
Lille, France
Institut Paoli Calmettes
Marseille, France
CHU de Nantes hotel Dieu
Nantes, France
Hopital Saint Louis
Paris, France
Institut Universitaire du Cancer Toulouse Oncopole
Toulouse, France
CHRU de Nancy - Hopitaux de Brabois
Vandœuvre-lès-Nancy, France
Klinikum Chemnitz gGmbH
Chemnitz, Germany
Universitatsklinikum Carl Gustav Carus Dresden
Dresden, Germany
University Hospital Hamburg Eppendorf
Hamburg, Germany
Klinikum Region Hannover Klinikum Siloah
Hanover, Germany
Uniklinikum Heidelberg
Heidelberg, Germany
Klinikum Nurnberg Nord
Nuremberg, Germany
Universitätsklinikum Würzburg Med. Klinik U. Poliklinik Ii
Würzburg, Germany
University Hospital of Alexandroupolis
Alexandroupoli, Greece
Laiko General Hospital of Athens
Athens, Greece