Evaluation of the Protective Efficacy of a Spatial Repellent to Reduce Malaria Prevalence in Uganda

Who May Qualify: Cluster level: Number of households \> 100 Household level: Presence of a child ≤ 5 years of age at point of enrolment in the study Adult head of household agrees to receiving and using the device as per manual instructions Adult head of household agrees to data collection visits and household surveys Children within household sleeps in cluster \> 90% of nights during any given month Individual level: ≤ 5 years of age when enrolled into the study No plans for extended travel (\> 1 month) outside of home during study Not participating in another clinical trial investigating a vaccine, drug, medical device, or a medical procedure during the trial Provision of willing to sign a consent form form (ICF) by the parent(s) or guardian Participants not on regular malaria prophylaxis Who Should NOT Join This Trial: Cluster level: Number of households \< 100 Household level: Presence of a child \> 5 years of age at point of enrolment in the study Adult head of household does not agree to data collection visits and household surveys Children within household sleeps in cluster \< 90% of nights during any given month Households where study personnel identify a security risk (i.e., site where drugs are sold, residents are always drunk or hostile). Individual level: \>5 years of age when enrolled into the study Plans for extended travel (\> 1 month) outside of home during study Participating or planned participation in another clinical trial investigating a vaccine, drug, medical device, or a medical procedure during the trial No provision of ICF signed by the parent(s) or guardian Participants on regular malaria prophylaxis Always talk to your doctor about whether this trial is right for you.