Molecular Imaging in Fabry Disease of the Heart

Who May Qualify: - Male or female participants \>18 years old - Able to give written, willing to sign a consent form and to lie flat - Have Fabry disease based on molecular diagnosis (at a minimum, documented enzyme deficiency in males and documented pathogenic mutation in females) - Cardiac MRI within 3 years documenting cardiac involvement in Fabry disease (left ventricular hypertrophy and/or late gadolinium enhancement and/or myocardial oedema) Who Should NOT Join This Trial: - Any other diagnosis associated with cardiac muscle inflammation, including myocarditis - Previous gene therapy - Contra-indication to MRI scanning or intravenous gadolinium contrast (prior contrast reaction or chronic kidney disease with eGFR \<30 mL/min/1.73 m2) - Women of child bearing potential not using adequate contraception - Uncontrolled atrial fibrillation - Any medical condition, in the opinion of the investigator, that prevents the participant from lying flat during scanning, or from participating in the study Always talk to your doctor about whether this trial is right for you.