Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises

Who May Qualify: - Adult (age \> 18 years) emergency department patient - History of sickle cell disease - Presenting to the emergency department due to acute pain related to sickle cell disease thought to be due to vaso-occlusive crisis Who Should NOT Join This Trial: - Prior enrollment in this study - Presenting with a chief complaint suggestive of a complicated crisis (such as concern for acute chest syndrome, splenic sequestration, hepatic sequestration, pulmonary embolism) as determined by the clinical care provider - Not being treated with intravenous opioids for the vaso-occlusive crisis - Patients who lack the capacity to provide willing to sign a consent form - Medical history of seizures or known intolerance to virtual reality - Disabilities like vision and hearing defects etc. that preclude the use of a head mounted virtual reality device. - Known to be pregnant - Incarcerated at the time of evaluation - Over the age of 89 years old Always talk to your doctor about whether this trial is right for you.