RECRUITINGINTERVENTIONAL
EUS-guided Celiac Plexus Block vs. Sham in Chronic Pancreatitis
Randomized Trial of EUS-guided Celiac Plexus Block vs. Sham for Palliation of Pain in Chronic Pancreatitis
About This Trial
The aim of this randomized trial is to assess the efficacy of EUS-CPB in the alleviation of abdominal pain in patients with chronic pancreatitis.
Who May Be Eligible (Plain English)
Who May Qualify:
- Age ≥ 18 years
- Abdominal pain of at least 3 months duration and a VAS score ≥ 3, with or without the use of narcotic analgesics.
- Diagnosis of chronic pancreatitis on EUS examination, with ≥ 5 features on EUS.
- No other cause of abdominal pain
Who Should NOT Join This Trial:
- Age \< 18 years.
- History of prior EUS-CPB.
- Use of anticoagulants that cannot be discontinued for the procedure.
- Clinically significant allergy to bupivacaine or triamcinolone.
- Unable to obtain consent for the procedure from either the patient or LAR.
- Intrauterine pregnancy.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Age ≥ 18 years
* Abdominal pain of at least 3 months duration and a VAS score ≥ 3, with or without the use of narcotic analgesics.
* Diagnosis of chronic pancreatitis on EUS examination, with ≥ 5 features on EUS.
* No other cause of abdominal pain
Exclusion Criteria:
* Age \< 18 years.
* History of prior EUS-CPB.
* Use of anticoagulants that cannot be discontinued for the procedure.
* Clinically significant allergy to bupivacaine or triamcinolone.
* Unable to obtain consent for the procedure from either the patient or LAR.
* Intrauterine pregnancy.
Treatments Being Tested
PROCEDURE
EUS-guided celiac plexus block
Under EUS-guidance, celiac plexus block will be performed with injection of bupivacaine and triamcinolone into the area of celiac plexus.
PROCEDURE
Sham procedure
Celiac plexus will not be performed in this arm.
Locations (1)
Orlando Health
Orlando, Florida, United States