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RECRUITINGINTERVENTIONAL

Effects of Eccentric Exercise Training in Patients With COPD

Effects of Smart Eccentric Exercise Training on Lymphocyte Immunity and Erythrocyte Rheology in Patients With Chronic Obstructive Pulmonary Disease

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The goal of this study is to design eccentric exercise strategies for COPD patients to comprehensively improve their cardiopulmonary/muscular fitness, immune and hemorheological functions, and quality of life, thereby improving the prognosis of their disease.

Who May Be Eligible (Plain English)

Who May Qualify: - Having undergone pulmonary rehabilitation for more than 3 months - Sign the written willing to sign a consent form form - FEV1/FVC \< 0.70 - Approval for exercise training granted by a specialist physician's assessment - Specialist physician's approval for exercise training Who Should NOT Join This Trial: - Existing of tracheostomy - Those who use oxygen therapy or ventilator at home - Severe heart failure (NYHA III-IV) - Neuromuscular disease - Acute exacerbation within the past three months - Those who are unable to cooperate with the cardiopulmonary exercise test - Taking anticoagulant medications - Other conditions restricting exercise for over a year - Recent or planned significant cardiovascular surgery or intervention - Current or planned pregnancy within the next year - Planned heart transplant within the next six months - Heart failure due to uncorrectable valvular heart disease, congenital heart disease or obstructive cardiomyopathy - Inadequate ICD settings for exercise heart rate - Other exercise contraindications: unstable angina, uncontrolled blood pressure, orthostatic hypotension with symptoms, severe aortic stenosis, acute discomfort or fever, uncontrolled arrhythmias, uncompensated heart failure, acute pericarditis or myocarditis, recent thrombosis or thrombophlebitis, resting ST-segment deviation, uncontrolled diabetes, etc. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Having undergone pulmonary rehabilitation for more than 3 months * Sign the written informed consent form * FEV1/FVC \< 0.70 * Approval for exercise training granted by a specialist physician's assessment * Specialist physician's approval for exercise training Exclusion Criteria: * Existing of tracheostomy * Those who use oxygen therapy or ventilator at home * Severe heart failure (NYHA III-IV) * Neuromuscular disease * Acute exacerbation within the past three months * Those who are unable to cooperate with the cardiopulmonary exercise test * Taking anticoagulant medications * Other conditions restricting exercise for over a year * Recent or planned significant cardiovascular surgery or intervention * Current or planned pregnancy within the next year * Planned heart transplant within the next six months * Heart failure due to uncorrectable valvular heart disease, congenital heart disease or obstructive cardiomyopathy * Inadequate ICD settings for exercise heart rate * Other exercise contraindications: unstable angina, uncontrolled blood pressure, orthostatic hypotension with symptoms, severe aortic stenosis, acute discomfort or fever, uncontrolled arrhythmias, uncompensated heart failure, acute pericarditis or myocarditis, recent thrombosis or thrombophlebitis, resting ST-segment deviation, uncontrolled diabetes, etc.

Treatments Being Tested

DEVICE

Eccentric bike

Received eccentric cycling exercise

OTHER

conventional group

Received conventional treatment

Locations (1)

Fu Jen Catholic University Hospital, Fu Jen Catholic University
New Taipei City, Taiwan