Skip to main content
TrialFinder
TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor about whether a trial is right for you.
RECRUITINGEarly Phase 1INTERVENTIONAL

Hormonal Responses to a Mixed Meal in People With Cystic Fibrosis

Changes in Postprandial Hormone Levels in Cystic Fibrosis Related Diabetes.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

In this exploratory study, the hormonal responses to a mixed meal will be examined in people with cystic fibrosis. The aim of this study is to find correlates with impaired glucose tolerance that is associated with this population.

Who May Be Eligible (Plain English)

Who May Qualify: - Diagnosed with cystic fibrosis - Aged 18 to 45 years - Males and females of any race and ethnicity - Receiving highly effective CFTR modular therapy Who Should NOT Join This Trial: - Transplant recipient - Acute lung function decline or exacerbation within the last 3 months - Use of systemic glucocorticoids - Pregnancy - Known liver disease that would be expected to significantly impact metabolic variable as interpreted by a study doctor - The presence of any other disease or condition, as interpreted by any one of the study doctors, that would be expected to confound the responses to liquid mixed meal or make participation in the study dangerous to the individual - People who are cognitively impaired - People who do not speak English - For CFRD patients, a daily insulin requirement that exceeds 0.8 U/kg/day - Any prior history of diabetic ketoacidosis. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Diagnosed with cystic fibrosis * Aged 18 to 45 years * Males and females of any race and ethnicity * Receiving highly effective CFTR modular therapy Exclusion Criteria: * Transplant recipient * Acute lung function decline or exacerbation within the last 3 months * Use of systemic glucocorticoids * Pregnancy * Known liver disease that would be expected to significantly impact metabolic variable as interpreted by a study doctor * The presence of any other disease or condition, as interpreted by any one of the study doctors, that would be expected to confound the responses to liquid mixed meal or make participation in the study dangerous to the individual * People who are cognitively impaired * People who do not speak English * For CFRD patients, a daily insulin requirement that exceeds 0.8 U/kg/day * Any prior history of diabetic ketoacidosis.

Treatments Being Tested

OTHER

Mixed meal

Each individual will ingest 5 mL/kg of Boost energy drink.

Locations (1)

University of Cincinnati
Cincinnati, Ohio, United States