RECRUITINGOBSERVATIONAL
Microbiome and Host Susceptibility in Severe Pneumonia, a Prospective, Multicenter, Cohort Study
Identification of Lung and Intestinal Microbiome and Host Susceptibility in Severe Pneumonia, a Prospective, Multicenter Cohort Study
About This Trial
This study was a prospective multicenter cohort of severe pneumonia. And by collecting clinical samples to clarify the correlation between lung microbiome, intestinal microbiome, host susceptibility, and prognosis of severe pneumonia patients.
Who May Be Eligible (Plain English)
Who May Qualify:
1\. New lung infection that meets one of the following definitions: the patient receives mechanical ventilation (invasive or non-invasive) due to acute respiratory failure, with a PEEP level of 5cm or above; Patients receiving high flow oxygen therapy with a FiO2 of 50% or more and a PaO2: FiO2 ratio below 300
Who Should NOT Join This Trial:
1. Expected length of stay in ICU is less than 1 day
2. Pregnant
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
1\. New lung infection that meets one of the following definitions: the patient receives mechanical ventilation (invasive or non-invasive) due to acute respiratory failure, with a PEEP level of 5cm or above; Patients receiving high flow oxygen therapy with a FiO2 of 50% or more and a PaO2: FiO2 ratio below 300
Exclusion Criteria:
1. Expected length of stay in ICU is less than 1 day
2. Pregnant
Treatments Being Tested
DIAGNOSTIC_TEST
Metagenomics
Clinical metagenomics is used to evaluate pathogens
Locations (15)
First Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
Shulan (Hangzhou) hospital
Hangzhou, China
Tongde Hospital of Zhejiang Province
Hangzhou, China
the First People's Hospital of Huzhou
Huzhou, China
The First Hospital of Jiaxing
Jiaxing, China
Lanxi Hospital of Traditional Chinese Medicine
Lanxi, China
Lishui People's Hospital
Lishui, China
The First People's Hospital of Pinghu
Pinghu, China
Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University
Taizhou, China
Wenzhou Central Hospital
Wenzhou, China
Xi'an People's Hospital (Xi'an No.4 Hospital)
Xi'an, China
Henan Provincial People's Hospital
Zhengzhou, China
The Fifth Clinical Medical College of Henan University of Chinese Medicine
Zhengzhou, China
The Second Affiliated Hospital of Zhengzhou University
Zhengzhou, China