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RECRUITINGINTERVENTIONAL

Oral Health and Adverse Pregnancy Complications

The Prevention of Adverse Pregnancy Outcomes by Periodontal Treatment (PROBE) Intervention Study

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Pregnant women are susceptible to develop periodontitis, but these oral health changes related to pregnancy are often neglected. Periodontitis is accompanied by a low-grade systemic inflammation and can be harmful to the general health of the woman, contribute to pre-term birth and adversely influence the future health and metabolism of the offspring. Despite this, studies indicate that 40% of Danish women in childbearing age do not visit a dentist regularly. The PROBE controlled intervention study will investigate the beneficial effect of treatment of periodontal disease during pregnancy on fetal growth, preterm delivery and birth weight.

Who May Be Eligible (Plain English)

Who May Qualify: - Pregnant women who are planned to give birth at either Holbaek or Nykoebing Falster hospital - Pregnant women diagnosed with periodontitis (stage I-III) by the study dentist Who Should NOT Join This Trial: - Pregnant women without peridontitis - Pregnant women with less than 20 healthy teeths - Pregnant women with peridontitis and currently receiving treatment for peridontitis - Pregnant women with peridontitis stage IV Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Pregnant women who are planned to give birth at either Holbaek or Nykoebing Falster hospital * Pregnant women diagnosed with periodontitis (stage I-III) by the study dentist Exclusion Criteria: * Pregnant women without peridontitis * Pregnant women with less than 20 healthy teeths * Pregnant women with peridontitis and currently receiving treatment for peridontitis * Pregnant women with peridontitis stage IV

Treatments Being Tested

OTHER

Periodontal treatment

Periodontal treatment

Locations (3)

Holbaek Hospital
Holbæk, Holbaek, Denmark
Holbæk Hospital
Holbæk, Holbaek, Denmark
Nykøbing Falster Hospital
Nykøbing Falster, Nykøbing Falster, Denmark