Use Of Indocyanine Green In Pancreas Surgery

Who May Qualify: - Participant scheduled for open pancreaticoduodenectomy or distal pancreatectomy for any diagnosis - Participant ≥ 18 years of age - Ability to understand nature and individual consequences of clinical trial - Written willing to sign a consent form from participant or legally authorized representative - For participants of childbearing potential, a negative pregnancy test and adequate contraception until 14 days after trial intervention - Participant needs to have an operative drain (any closed suction drain) after the procedure - Participants that do not require arterial reconstruction - Participants that require minor portal venous recounstructions including patch venoplasty Who Should NOT Join This Trial: - Patients with previous history of adverse reaction to contrast dye, ICG or components of the dye - Prior pancreatectomy - Known diagnosis of hepatic insufficiency, hepatitis, liver fibrosis or cirrhosis, or chronic pancreatitis - Because this study focuses on hypoperfusion, patients will be excluded if in postoperative day 3-5 had any of the following: persistent SBP \<90 mmHg unresponsive to 1L crystalloid, unexpected ICU transfer, blood transfusion of \>2 units intraoperatively or 1 postoperatively, vasopressor treatment or ACLS protocol initiation - Organ failure, anuria or NSQIP-identified complication will be reviewed by PI and attending surgeon and excluded - Patients that require arterial reconstruction as part of their procedures Always talk to your doctor about whether this trial is right for you.