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RECRUITINGINTERVENTIONAL

Hemodynamic Effect of Nasal High-flow in Patients Suspected or Followed for a Precapillary Pulmonary Hypertension

Physiological Evaluation of the Hemodynamic Effects of Nasal High Flow in Patients Being Explored by Right Heart Catheterisation and Echocardiography for Suspected or Followed Precapillary Pulmonary Hypertension

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

In this study, the investigators aim to describe the hemodynamic consequences of nasal high-flow measured during right heart catheterization and echocardiography. The research hypothesis is that nasal high-flow would increase cardiac output in patients with pulmonary hypertension. The concomitant echocardiography will allow to describe its sensibility to detect cardiovascular consequences of nasal high-flow.

Who May Be Eligible (Plain English)

Who May Qualify: \- patient addressed for right heart catheterization for pulmonary hypertension suspicion or follow-up. Who Should NOT Join This Trial: - necessity of FiO2 \>21% during right heart catheterization - intracardiac shunt - grade 4 tricuspid insufficiency - complete arrhythmia due to atrial fibrillation - Pregnant or breastfeeding women or women of childbearing age without an effective method of contraception - protected adult patient (tutorship or curatorship) - patient deprived of liberty by court or administrative decision - refusal of patient participation or consent - patient for whom the measurement of pulmonary arterial pressures during right heart catheterization is impossible - patient for whom, during the etiological assessment of pulmonary hypertension, the diagnosis of precapillary pulmonary hypertension cannot be confirmed and classified in groups 1, 3 or 4. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: \- patient addressed for right heart catheterization for pulmonary hypertension suspicion or follow-up. Exclusion Criteria: * necessity of FiO2 \>21% during right heart catheterization * intracardiac shunt * grade 4 tricuspid insufficiency * complete arrhythmia due to atrial fibrillation * Pregnant or breastfeeding women or women of childbearing age without an effective method of contraception * protected adult patient (tutorship or curatorship) * patient deprived of liberty by court or administrative decision * refusal of patient participation or consent * patient for whom the measurement of pulmonary arterial pressures during right heart catheterization is impossible * patient for whom, during the etiological assessment of pulmonary hypertension, the diagnosis of precapillary pulmonary hypertension cannot be confirmed and classified in groups 1, 3 or 4.

Treatments Being Tested

DEVICE

Nasal high-flow

Nasal high-flow is a respiratory technique which allows the administration of warmed and humidified air, associated with oxygen if necessary

Locations (1)

ROUEN university hospital
Rouen, France