RECRUITINGPhase 2 / Phase 3INTERVENTIONAL
Faecal Microbiota Transplantation as Means of Preventing Recurrent Urinary Tract Infections
About This Trial
This study investigates Faecal microbiota transplantation (FMT) in prevention of recurrent urinary tract infections (UTIs) caused either by sensitive E. coli or ESBL-E. coli.
Who May Be Eligible (Plain English)
Who May Qualify:
- Female subjects aged ≥18
- History of recurrent UTI: at least two episodes of UTI over the past 6 months or at least three episodes over the past year, most recent episode within the past three months
- Written willing to sign a consent form
Who Should NOT Join This Trial:
- Suspected non-compliance
- Diagnosis of a gastrointestinal disease
- Pregnancy
- Immunosuppression
- Any kind of permanent urinary catheter or intermittent urinary catheterization
- Any other criteria which, in the investigator's opinion, would compromise the ability of the subject to participate in the study, the subject's well-being, or the outcome of the study
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion criteria:
* Female subjects aged ≥18
* History of recurrent UTI: at least two episodes of UTI over the past 6 months or at least three episodes over the past year, most recent episode within the past three months
* Written informed consent
Exclusion criteria:
* Suspected non-compliance
* Diagnosis of a gastrointestinal disease
* Pregnancy
* Immunosuppression
* Any kind of permanent urinary catheter or intermittent urinary catheterization
* Any other criteria which, in the investigator's opinion, would compromise the ability of the subject to participate in the study, the subject's well-being, or the outcome of the study
Treatments Being Tested
BIOLOGICAL
Feacal microbial transplantation (FMT)
Feacal microbial transplantation (FMT)
OTHER
Placebo transplantation (PT)
Transplantation with coloured 0,9% NaCl-solution
Locations (1)
Meilahti Vaccine Research Center, Helsinki University Central Hospital
Helsinki, Finland