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RECRUITINGPhase 2 / Phase 3INTERVENTIONAL

Faecal Microbiota Transplantation as Means of Preventing Recurrent Urinary Tract Infections

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This study investigates Faecal microbiota transplantation (FMT) in prevention of recurrent urinary tract infections (UTIs) caused either by sensitive E. coli or ESBL-E. coli.

Who May Be Eligible (Plain English)

Who May Qualify: - Female subjects aged ≥18 - History of recurrent UTI: at least two episodes of UTI over the past 6 months or at least three episodes over the past year, most recent episode within the past three months - Written willing to sign a consent form Who Should NOT Join This Trial: - Suspected non-compliance - Diagnosis of a gastrointestinal disease - Pregnancy - Immunosuppression - Any kind of permanent urinary catheter or intermittent urinary catheterization - Any other criteria which, in the investigator's opinion, would compromise the ability of the subject to participate in the study, the subject's well-being, or the outcome of the study Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion criteria: * Female subjects aged ≥18 * History of recurrent UTI: at least two episodes of UTI over the past 6 months or at least three episodes over the past year, most recent episode within the past three months * Written informed consent Exclusion criteria: * Suspected non-compliance * Diagnosis of a gastrointestinal disease * Pregnancy * Immunosuppression * Any kind of permanent urinary catheter or intermittent urinary catheterization * Any other criteria which, in the investigator's opinion, would compromise the ability of the subject to participate in the study, the subject's well-being, or the outcome of the study

Treatments Being Tested

BIOLOGICAL

Feacal microbial transplantation (FMT)

Feacal microbial transplantation (FMT)

OTHER

Placebo transplantation (PT)

Transplantation with coloured 0,9% NaCl-solution

Locations (1)

Meilahti Vaccine Research Center, Helsinki University Central Hospital
Helsinki, Finland