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RECRUITINGINTERVENTIONAL

Effectiveness of Trauma Therapy Using Prolonged Exposure for Patients With PTSD and a Comorbid Psychotic Disorder

How Effective and Safe is Trauma Therapy Using Prolonged Exposure for Patients With PTSD and a Comorbid Psychotic Disorder? Treatment Trauma and Psychosis -TEP

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Psychosis patients with comorbid PTSD will be treated with trauma therapy.

Who May Be Eligible (Plain English)

Who May Qualify: - Presence of a psychotic disorder (F20) or affective disorder with psychotic symptoms(F30) according to DSM-5. - comorbid post-traumatic stress disorder (PTSD) according to DSM-5 (CAPS-5 score ≥ 23) - At least 18 years old - Good knowledge of the German language - Willingness to participate in randomisation and trauma-focused therapy Who Should NOT Join This Trial: - Changes in neuroleptic or antidepressant therapy within the last 4 weeks (exclusion of drug effects). - Any substance dependence with continued use other than nicotine and/or caffeine dependence. - IQ of 70 or less - Acute suicidality - Pregnant women Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Presence of a psychotic disorder (F20) or affective disorder with psychotic symptoms(F30) according to DSM-5. * comorbid post-traumatic stress disorder (PTSD) according to DSM-5 (CAPS-5 score ≥ 23) * At least 18 years old * Good knowledge of the German language * Willingness to participate in randomisation and trauma-focused therapy Exclusion Criteria: * Changes in neuroleptic or antidepressant therapy within the last 4 weeks (exclusion of drug effects). * Any substance dependence with continued use other than nicotine and/or caffeine dependence. * IQ of 70 or less * Acute suicidality * Pregnant women

Treatments Being Tested

BEHAVIORAL

Prolonged Exposure

In the intervention condition, patients are treated directly after the baseline measurement by Prolonged Exposure in 16 hours of individual therapy. The 16 individual therapy sessions will take place in 1 to 2 sessions per week over a period of 7 to 16 weeks. The individual therapy sessions are videotaped with camera focus on the therapist. Parts of the Prolonged Exposure process (the re-experiencing of the traumatic memory) are recorded on tape, so that the patient can listen to the recording as homework at home. Afterwards, the patients take part in a study diagnostic session.

Locations (1)

Medicalschool Hamburg
Hamburg, Germany