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RECRUITINGINTERVENTIONAL

Comparison of Self- and Balloon-expandable Valves in Patients With Ascending Aortic Dilation Undergoing Transcatheter Aortic Valve Replacement: The AAD-CHOICE

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This study aimed at comparing the performance of self-expandable valves versus balloon-expandable valves in patients with ascending aortic dilation undergoing transcatheter aortic valve replacement.

Who May Be Eligible (Plain English)

Who May Qualify: - Severe aortic stenosis; - Transfemoral access; - Preoperative aortic CT suggesting maximum ascending aortic diameter ≥45mm and \<55mm; - Anticipated life expectancy \>1 year; - Age ≥ 65 years. Who Should NOT Join This Trial: - Dominant aortic regurgitation,; - A history of SAVR or TAVR; - A history of aortic surgery; - Emergent TAVR. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Severe aortic stenosis; * Transfemoral access; * Preoperative aortic CT suggesting maximum ascending aortic diameter ≥45mm and \<55mm; * Anticipated life expectancy \>1 year; * Age ≥ 65 years. Exclusion Criteria: * Dominant aortic regurgitation,; * A history of SAVR or TAVR; * A history of aortic surgery; * Emergent TAVR.

Treatments Being Tested

DEVICE

self-expandable valves

patients undergoing TAVR use self-expandable valves

DEVICE

balloon-expandable valves

patients undergoing TAVR use balloon-expandable valves

Locations (1)

National Center for Cardiovascular Disease, China & Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing, Beijing Municipality, China