Skip to main content
TrialFinder
TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor about whether a trial is right for you.
RECRUITINGOBSERVATIONAL

The Daytime Circadian Rhythm in Exhaled Volatile Organic Compounds in People Living Without and Diabetes

The Daytime Circadian Rhythm in Exhaled Volatile Organic Compounds in People Living Without and With Type 1 and 2 Diabetes: an Exploratory Study

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Exhaled volatile organic compounds will be measured during daytime with the goal to identifying circadian variability. The study incudes three subgroups: people without diabetes, people with type 1 diabetes, and people with type 2 diabetes. A total of 60 people will be recruited for the study.

Who May Be Eligible (Plain English)

Inclusion criteria Subgroup 1: - Age 18 or older - HbA1c below 6.5% - Written willing to sign a consent form Subgroup 2: - Age 18 or older - T1D (Type 1 diabetes) with MDI (multiple daily injection) or CSII (Continuous subcutaneous insulin infusion therapy) therapy \>1 year - Written willing to sign a consent form Subgroup 3 - Age 18 or older - T2D (Type 2 diabetes) with oral antidiabetic medication or insulin therapy - Written willing to sign a consent form Exclusion criteria - Pregnancy or breastfeeding - Smoking (last cigarette less than 6 months ago) - Any chronical lung and intestinal disease diagnosis (such as intestinal bowel disease (IBD); asthma; COPD (chronic obstructive pulmonary disease); lung cancer, …) - Coeliac disease - Lactose and fructose intolerance - Any acute disease diagnosis (such as viral or bacterial infection) - Drinking habit of more than four units of alcohol per day - Current inhaled medicines treatments - Antibiotic treatment in the previous 4 months Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion criteria Subgroup 1: * Age 18 or older * HbA1c below 6.5% * Written informed consent Subgroup 2: * Age 18 or older * T1D (Type 1 diabetes) with MDI (multiple daily injection) or CSII (Continuous subcutaneous insulin infusion therapy) therapy \>1 year * Written informed consent Subgroup 3 * Age 18 or older * T2D (Type 2 diabetes) with oral antidiabetic medication or insulin therapy * Written informed consent Exclusion criteria * Pregnancy or breastfeeding * Smoking (last cigarette less than 6 months ago) * Any chronical lung and intestinal disease diagnosis (such as intestinal bowel disease (IBD); asthma; COPD (chronic obstructive pulmonary disease); lung cancer, …) * Coeliac disease * Lactose and fructose intolerance * Any acute disease diagnosis (such as viral or bacterial infection) * Drinking habit of more than four units of alcohol per day * Current inhaled medicines treatments * Antibiotic treatment in the previous 4 months

Treatments Being Tested

OTHER

Standardized meal

The participants will receive a standardized meal for breakfast

Locations (1)

University of Bern
Bern, Switzerland