RECRUITINGOBSERVATIONAL
Dynamic Parameters of Glucose Control in Relation to Biomarkers in Serum and Intraocular Fluid in Patients With Diabetes
Dynamic Parameters of Glucose Control in Relation to Biomarkers in Serum and Intraocular Fluid in Diabetic Patients With Ocular Complications
About This Trial
Our project investigates the new characteristics of diabetic retinopathy using liquid eye biopsy in combination with novel parameters of glucose control obtained with continuous glucose monitoring. This approach will bring new knowledge and implications for future therapies.
Who May Be Eligible (Plain English)
Who May Qualify:
- type 1 or type 2 diabetes
- ≥ 18 years old
- treatment with insulin for at least 5 years prior baseline
- any form of diabetic retinopathy and macular edema
- HbA1c \< 10%
- written willing to sign a consent form prior to starting study related activity
Who Should NOT Join This Trial:
- any active intraocular or periocular infectious or non-infectious inflammation in study eye
- uncontrolled glaucoma
- history of intraocular inflammation or trauma in study eye
- intravitreal anti-VEGF therapy in study eye during a 3-month perido prior to baseline
- use of corticosteroid intravitreal implant in study eye at any time
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* type 1 or type 2 diabetes
* ≥ 18 years old
* treatment with insulin for at least 5 years prior baseline
* any form of diabetic retinopathy and macular edema
* HbA1c \< 10%
* written informed consent prior to starting study related activity
Exclusion Criteria:
* any active intraocular or periocular infectious or non-infectious inflammation in study eye
* uncontrolled glaucoma
* history of intraocular inflammation or trauma in study eye
* intravitreal anti-VEGF therapy in study eye during a 3-month perido prior to baseline
* use of corticosteroid intravitreal implant in study eye at any time
Treatments Being Tested
PROCEDURE
Intraocular surgery
Pars plana vitrectomy or cataract surgery.
Locations (1)
General University Hospital in Prague
Prague, Czechia