Registry of X-linked Adrenoleukodystrophy

Who May Qualify: X-ALD group： - Meet the diagnostic criteria of X-ALD and supported by the results of genetic and very long chain fatty acid (VLCFA) test; - Age: 6 - 70 years old; - Able to communicate normally, and complete the test of scale as instructed (confirmed by the field test of scale); - Sign the willing to sign a consent form. Carrier-control group: Healthy people who have no significant difference in age, sex and education comparing with the X-ALD group, volunteer to participate in this study, could complete the test of scale as instructed, and meet the following criteria: - Eligible for asymptomatic carriers in genetic tests (preference of patient's mother and close relatives); - Age: 6 - 70 years old, able to complete the test of scale as instructed (confirmed by the field test of scale); - No history of psychiatric diseases. Who Should NOT Join This Trial: - Other hereditary diseases; - Other severe central nervous diseases; - History of surgery of brain or eye; - Psychiatric and psychological diseases, such as anxiety and depression; - Metal foreign body or prosthesis in the human body (such as pacemaker and insulin pump), claustrophobia, and other MRI contraindications; - History of surgery associated with gastrointestinal tract; - No willing to sign a consent form; - Unable to tolerate MRI or eye related tests. Always talk to your doctor about whether this trial is right for you.