RECRUITINGOBSERVATIONAL

Biocollection on Peripheral Inflammation

Biocollection on Peripheral Inflammation in Psychiatric Pathologies

About This Trial

Most psychiatric research is based on the nosographic classifications used in current practice. At present, there is no diagnostic or prognostic biomarker for psychiatric pathologies commonly used in clinical practice. The study hypothesis is that peripheral inflammatory biomarkers could be common to several psychiatric disorders, in particular psychotic disorders (bipolar disorder, schizophreniform disorder, schizophrenia, depressive episode with psychotic features). The aim of this project is to set up a bio-collection of biological samples (peripheral blood samples) with associated phenotypic data (assessment of various symptoms using standardized scales in patients whose blood is sampled). The setting up of this cohort follows on from work carried out on a PsyCourse cohort also using a transdiagnostic approach in psychiatry, in order to be able to collaborate within a European research project.

Who May Be Eligible (Plain English)

Who May Qualify: - Major patient - Patient with one of the following diagnoses confirmed by a psychiatrist: - Characterized depressive episode with psychotic features, - Bipolar disorder type I - Bipolar disorder type II - Schizoaffective disorder - Schizophrenia - Schizophreniform disorder - Patient under psychiatric care at Nantes University Hospital - Patients weighing at least 45kg - Patient affiliated to a social security scheme or beneficiary of such a scheme - Patient who has given willing to sign a consent form to participate in the study Who Should NOT Join This Trial: - Pregnant, - History of cancer in the last 5 years, - Vaccination within the last 4 weeks, - Acute or chronic infection, - Medical history of organ transplant, - Medical history of autoimmune conditions (where your immune system attacks your own body), - Hearing impairment making it impossible to complete study questionnaires, - Patient under court protection Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Inclusion Criteria: * Major patient * Patient with one of the following diagnoses confirmed by a psychiatrist: * Characterized depressive episode with psychotic features, * Bipolar disorder type I * Bipolar disorder type II * Schizoaffective disorder * Schizophrenia * Schizophreniform disorder * Patient under psychiatric care at Nantes University Hospital * Patients weighing at least 45kg * Patient affiliated to a social security scheme or beneficiary of such a scheme * Patient who has given informed consent to participate in the study Exclusion Criteria: * Pregnant, * History of cancer in the last 5 years, * Vaccination within the last 4 weeks, * Acute or chronic infection, * Medical history of organ transplant, * Medical history of autoimmune disease, * Hearing impairment making it impossible to complete study questionnaires, * Patient under court protection

Treatments Being Tested

BIOLOGICAL

Peripheral venipuncture blood sampling, as part of standard care procedures

Collection of 36 mL of blood

OTHER

Interview with a psychiatrist

Research project data collection

Locations (1)

Nantes University Hospital

Nantes, France