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RECRUITINGINTERVENTIONAL

Mitigating the Impact of Stigma and Shame Among People Living With HIV and Substance Use Disorders

Mitigating the Impact of Stigma and Shame as a Barrier to Viral Suppression Among People Living With HIV and Substance Use Disorders

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

People living with HIV and substance use disorders (SUDs) are less likely to be virally suppressed, which can lead to HIV transmission and negative health outcomes. This hybrid type 1 study will assess the efficacy, mechanisms, as well as facilitators and barriers to implementing the MATTER intervention, a virtually delivered 5-session text-enhanced psychobehavioral intervention designed to facilitate viral suppression by addressing internalized stigma and shame as barriers to engagement in HIV care among individuals living with HIV and SUDs in two locations with different levels of HIV resources (i.e., the Boston, Massachusetts and Miami, Florida metro areas). MATTER aims to mitigate the negative behavioral consequences of internalized stigma and shame on viral suppression by a) developing behavioral self-care goal setting skills and related self-efficacy, b) increasing metacognitive awareness (i.e., non-judgmental awareness of emotions and cognitions), and c) teaching and reinforcing compassionate self-restructuring (i.e., self- compassion), in addition to providing access to phone-based resource navigation. Scalable interventions such as MATTER are essential to our efforts to end the HIV epidemic in high priority regions.

Who May Be Eligible (Plain English)

Who May Qualify: - HIV+ - Meet criteria for an illicit (not solely including tobacco, cannabis, or alcohol) SUD - Endorse internalized stigma related to HIV, substance use, sexual orientation, or gender-identity - Unsuppressed HIV VL (\>20 copies/mL). - Provide willing to sign a consent form in English - Verbally communicate in English and read in English or Spanish - Be ≥18 years old - Provide evidence or documentation of HIV+ status - Release HIV-related health records - Have access to a cell phone with text capacity (study will supplement phones and plans as needed consistent with our pilot work). Who Should NOT Join This Trial: - Cisgender women - Cisgender heterosexual men Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * HIV+ * Meet criteria for an illicit (not solely including tobacco, cannabis, or alcohol) SUD * Endorse internalized stigma related to HIV, substance use, sexual orientation, or gender-identity * Unsuppressed HIV VL (\>20 copies/mL). * Provide informed consent in English * Verbally communicate in English and read in English or Spanish * Be ≥18 years old * Provide evidence or documentation of HIV+ status * Release HIV-related health records * Have access to a cell phone with text capacity (study will supplement phones and plans as needed consistent with our pilot work). Exclusion Criteria: * Cisgender women * Cisgender heterosexual men

Treatments Being Tested

BEHAVIORAL

Matter Intervention

This 5-session text-enhanced intervention is designed to mitigate the negative behavioral consequences of internalized stigma and shame among individuals with SUDs that perpetuate sub-optimal engagement in HIV self-care and consequently inconsistent viral suppression. The intervention involves five virtually delivered one-on-one therapy sessions focused on behavioral goal setting skill development and related self-efficacy, increasing meta-cognitive awareness (i.e., non-judgmental awareness of emotions and cognitions), and teaching and reinforcing compassionate self-restructuring (i.e., self-compassion). Participants also receive daily text messages querying emotions during the one-on-one portion of the intervention. For eight weeks after the one-on-one portion, participants receive their compassionate self-statements via text in response to their indicated emotions. Participants will also receive phone-based resource navigation, as needed.

BEHAVIORAL

Control Condition

The control condition will involve five sessions of prerecorded asynchronous content related to local resources (e.g., information related to substance use treatment and other ancillary services).

Locations (2)

Florida International University
Miami, Florida, United States
Fenway Health
Boston, Massachusetts, United States