Skip to main content
TrialFinder
TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor about whether a trial is right for you.
RECRUITINGINTERVENTIONAL

Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD

Pilot Feasibility Proposal to Adapt Trauma-focused Psychodynamic Psychotherapy (TFPP) for PLWH and PTSD

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

People living with HIV (PLWH) have a higher rate of post-traumatic stress disorder (PTSD) diagnosis than the general population. Comorbid PTSD is also associated with negative HIV-related health outcomes. Unfortunately, little outcome research has examined the usefulness of PTSD treatments for PTSD. This pilot study adapts for PLWH a non-exposure based psychotherapy for PTSD focused on reflecting on one's emotions and relationships and understanding and working through how trauma may have disrupted them. The study team is interested in better understanding the needs of PLWH with PTSD, learning whether PLWH with PTSD find this treatment acceptable and helpful, and beginning to understand the relationship between HIV-related health factors (e.g., inflammation and stress biology) and PTSD, and how these health factors may improve during treatment.

Who May Be Eligible (Plain English)

Who May Qualify: - Diagnosis of DSM-5 defined PTSD, per the Clinician Administered PTSD Scale \& CAPS-5 total severity score greater than or equal to 25 - HIV diagnosis (by medical records or HIV testing) - Stable psychiatric/psychotropic medication for \>=2 months and ongoing during treatment Who Should NOT Join This Trial: - Psychosis - Bipolar I - Acute suicidality - Current substance use disorder - Organic mental syndrome or intellectual disability - Unstable non-HIV medical conditions Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Diagnosis of DSM-5 defined PTSD, per the Clinician Administered PTSD Scale \& CAPS-5 total severity score greater than or equal to 25 * HIV diagnosis (by medical records or HIV testing) * Stable psychiatric/psychotropic medication for \>=2 months and ongoing during treatment Exclusion Criteria: * Psychosis * Bipolar I * Acute suicidality * Current substance use disorder * Organic mental syndrome or intellectual disability * Unstable non-HIV medical conditions

Treatments Being Tested

BEHAVIORAL

Trauma-focused psychodynamic psychotherapy

This psychotherapy addresses disruptions in the ability to reflect and affective regulation by exploring the psychological meanings of symptoms and their relation to traumatic events. The therapist works to identify intrapsychic conflicts, intense negative affects, and defense mechanisms related to the PTSD syndrome using a psychodynamic formulation that provides a framework for intervention. The transference provides a forum for patients to address feelings of mistrust, difficulties with authority, fears of abuse, angry and guilty feelings, and fantasies. This treatment will be provided in-person or over teletherapy as the public health situation demands.

Locations (1)

Albert Einstein College of Medicine
The Bronx, New York, United States