RECRUITINGINTERVENTIONAL

Peer-led Implementation of TB-HIV Education and Adherence Counseling in Uganda

About This Trial

This cluster-randomized trial in Uganda will evaluate the effectiveness and implementation of a novel, peer-led TB education and counseling strategy to improve outcomes among persons with tuberculosis (TB) with and without HIV/AIDS and assess the social-behavioral mechanisms underlying the observed treatment effects.

Who May Be Eligible (Plain English)

Who May Qualify: - Age ≥18 years - Registered as a new, relapse, treatment failure, or previously lost-to-follow-up - TB case according to the on-site NTP TB Treatment Register - Screened and invited to participate within 30 days of TB treatment initiation Who Should NOT Join This Trial: - Diagnosed with possible or confirmed drug-resistant TB - Transferring TB care into the clinic from an off-site facility - Residing \>40 km from the enrolling clinic - Lacking mental capacity to provide willing to sign a consent form Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Inclusion Criteria: * Age ≥18 years * Registered as a new, relapse, treatment failure, or previously lost-to-follow-up * TB case according to the on-site NTP TB Treatment Register * Screened and invited to participate within 30 days of TB treatment initiation Exclusion Criteria: * Diagnosed with possible or confirmed drug-resistant TB * Transferring TB care into the clinic from an off-site facility * Residing \>40 km from the enrolling clinic * Lacking mental capacity to provide informed consent

Treatments Being Tested

BEHAVIORAL

Peer-Navigaton TB-EC Strategy

Participants receive a peer-navigation strategy for TB education and counseling, including individual-level components such as peer navigator support, an illustrated TB-EC booklet with checklist, individualized adherence planning, and behavior-change messaging; and clinic-level components such as task-sharing with peer navigators, workflow restructuring, community of practice meetings, and implementation champions to support delivery.

BEHAVIORAL

Usual TB-EC Strategy

Participants receive usual TB education and counseling delivered by healthcare workers, including individual-level components such as TB-HIV education using a flipchart and use of treatment supporters; and clinic-level components such as routine TB-EC delivery by healthcare workers.

Locations (1)

Walimu

Kampala, Uganda