RECRUITINGPhase 2INTERVENTIONAL
Vitamin C Effectiveness in Preventing Urinary Tract Infections After Gynecological Surgeries
Vitamin C for the Prevention of Catheter-associated Urinary Tract Infections in Women Who Undergo Elective Gynecological Surgeries: a Randomized Double-blinded Controlled Trial
About This Trial
Double-blind placebo-controlled randomized trial aiming to assess the role of Vitamin C supplementation in the prevention of catheter-associated urinary tract infections in women undergoing elective gynecological surgeries.
Who May Be Eligible (Plain English)
Who May Qualify:
- Nonpregnant women
- 18 years of age or older
- Undergoing elective GYN surgery
Who Should NOT Join This Trial:
- Pregnant women
- Already taking Vitamin C supplementation
- Nephrolithiasis
- Congenital anomaly or neurogenic bladder
- Allergy to ascorbic acid
- On therapeutic anticoagulant medicine during the 6 weeks after surgery
- Gynecological surgery involving fistula repair or a vaginal mesh removal
- Positive Urinalysis in the pre-admission unit
- Recurrent UTIs
- Diabetes
- G6PD
- Hemochromatosis
- Renal disorders
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Nonpregnant women
* 18 years of age or older
* Undergoing elective GYN surgery
Exclusion Criteria:
* Pregnant women
* Already taking Vitamin C supplementation
* Nephrolithiasis
* Congenital anomaly or neurogenic bladder
* Allergy to ascorbic acid
* On therapeutic anticoagulant medicine during the 6 weeks after surgery
* Gynecological surgery involving fistula repair or a vaginal mesh removal
* Positive Urinalysis in the pre-admission unit
* Recurrent UTIs
* Diabetes
* G6PD
* Hemochromatosis
* Renal disorders
Treatments Being Tested
DRUG
Ascorbic Acid 1000 MG
1000mg Ascorbic acid orally daily started on the day of elective gynecological surgery for 10 days
DRUG
Placebo
Placebo tablet daily starting day of elective gynecological surgery for 10 days
Locations (1)
Moscow State University of Medicine and Dentistry
Moscow, Russia