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RECRUITINGINTERVENTIONAL

Trial of an Exercise Intervention for Children With Haemophilia

Development Of a haemophiLia PHysiotherapy INtervention for Optimum Musculoskeletal Health in Children (DOLPHIN-II) - a Randomised Controlled Trial

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

"Being able to participate in games and activities with their friends" is one of the things that matters most to boys with haemophilia. At present, there is a lack of robust evidence to determine whether muscle strengthening exercise can improve or negatively affect outcomes for young children with haemophilia. With the help of boys with haemophilia, their parents and physiotherapists the investigators have developed an exercise programme designed to increase muscle strength. Using this intervention the investigators will undertake a single-blinded, two-arm pragmatic randomised controlled trial (RCT) of a 12-week intervention verses usual care of boys with haemophilia aged 6-12 years of age.

Who May Be Eligible (Plain English)

Who May Qualify: • Children aged 6-12 years, with severe or moderate haemophilia A or B Who Should NOT Join This Trial: - von Willebrand disease - past history of fracture or trauma to the lower limb - orthopaedic surgery - acquired brain injury or any other disturbance of the central nervous system; joint or muscle bleed in the lower limb in the past 6 weeks - presence of lower limb pain or unable to fully comply with verbal instructions. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: • Children aged 6-12 years, with severe or moderate haemophilia A or B Exclusion Criteria: * von Willebrand disease * past history of fracture or trauma to the lower limb * orthopaedic surgery * acquired brain injury or any other disturbance of the central nervous system; joint or muscle bleed in the lower limb in the past 6 weeks * presence of lower limb pain or unable to fully comply with verbal instructions.

Treatments Being Tested

OTHER

Exercise

12-week exercise intervention

OTHER

Usual Care

usual care

Locations (1)

Haemophilia Centre
Canterbury, Kent, United Kingdom