Circulating Biomarker Signatures for the Detection of Gastric Preneoplasia and Cancer

Who May Qualify: Common - 18 years old or highter - written willing to sign a consent form prior to any study procedure - Affiliated to a social insurance system Specific to patients with gastric lesions - Untreated glandular atrophy (with or without intestinal metaplasia and/or dysplasia) and histologically diagnosed as of 2014 - Treatment naïve Gastric cancer (distal or proximal adenocarcinoma) Who Should NOT Join This Trial: Common - autoimmune conditions (where your immune system attacks your own body) or disease that impacts the immune system (e.g: HIV) - Chronic inflammatory disease - Known evolutive cancer (excluding gastric cancer) - Treated in the last 3 months or currently treated with therapy that interferes with the immune system (e.g. immunosuppressive therapy) - Current treatment with long-term corticosteroid therapy - Current treatment with long-term nonsteroidal anti-inflammatory drugs - Pregnant woman or breastfeeding - Patient or healthy volunteer under legal protection (e.g. guardianship) - Patient or healthy volunteer currently participating to a clinical trial evaluating either an experimental medical product or a medical device - Patient or healthy volunteer currently in custody Specific to Healthy Volunteer - Known history of Helicobacter pylori infection - Known history of gastric lesions (i.e. chronic gastritis, gastric atrophy, intestinal metaplasia, dysplasia and cancer) Always talk to your doctor about whether this trial is right for you.