RECRUITINGINTERVENTIONAL
Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Marfan Syndrome
Marfan&Moves (M&M's) : an Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Marfan Syndrome: an Interventional, Prospective, Monocentric Study.
About This Trial
This research study aims to evaluate the effect of a 6-month adapted physical activity program (APA) on the endurance capacities (evaluated as the maximum oxygen consumption \[VO2 peak\] on a cardiopulmonary exercise test) of children and adolescents with Marfan syndrome or related.
Who May Be Eligible (Plain English)
Who May Qualify:
- Genetically confirmed Marfan syndrome or related syndrome
- Girl or boy aged 7 to 17
- Informed and written consent signed by at least one of the two holders of parental authority
- Patient affiliated to a social security scheme or equivalent
Who Should NOT Join This Trial:
- Cardiac contraindications to the APA program:
- Severe aortic dilation (aortic diameter \> 45 mm)
- and/or left ventricular failure (left ventricular ejection fraction \<45%)
- and/or severe mitral leakage ≥ grade 3
- Pregnancy
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Genetically confirmed Marfan syndrome or related syndrome
* Girl or boy aged 7 to 17
* Informed and written consent signed by at least one of the two holders of parental authority
* Patient affiliated to a social security scheme or equivalent
Exclusion Criteria:
* Cardiac contraindications to the APA program:
* Severe aortic dilation (aortic diameter \> 45 mm)
* and/or left ventricular failure (left ventricular ejection fraction \<45%)
* and/or severe mitral leakage ≥ grade 3
* Pregnancy
Treatments Being Tested
OTHER
Adapted Physical Activity program
The Adaptated Physical Activity program will consist of a Personalized Training Program
Locations (1)
CHU Toulouse
Toulouse, France