A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)

Who May Qualify: - Documented diagnosis of PKU per local standard of care - Currently receiving or planned to receive pegvaliase treatment within 30 days after the date of enrollment, including subjects who previously received pegvaliase as part of the clinical development program and have completed study participation. - Subject (or legally authorized representative) is willing and able to provide written willing to sign a consent form after the nature of the study has been explained and prior to any data collection. Who Should NOT Join This Trial: - Subject has any kind of disorder that, in the opinion of the investigator, may compromise the ability of the subject to give written willing to sign a consent form and/or comply with any aspect of the study. - Currently participating in an interventional study of any investigational product, device, or procedure - Previously enrolled in this study (eg, subjects who have been withdrawn from the study and wish to participate again at a later date) - German subjects \<16 years if age Always talk to your doctor about whether this trial is right for you.