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RECRUITINGINTERVENTIONAL

Peer Interventions for Preschoolers With Autism

Examining Adaptive Peer-mediated Interventions for Preschoolers With Autism Spectrum Disorder and Limited or no Spoken Language: A Sequential Multiple Assignment Randomized Trial

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This proposal will evaluate a series of peer-mediated interventions (PMIs) for preschool children (3 to 6 years) with ASD and limited or no spoken language, using an innovative Sequential Multiple Assignment Randomized Trial (SMART) design. Available evidence supports the beneficial effects of PMIs for improving social communication in children with ASD. Peer-related social competence is vital to a wide range of child outcomes, such as improved communication and fewer behavioral problems. Unfortunately, approximately 30% of children with ASD remain minimally-verbal in kindergarten, restricting participation in inclusive activities. Recent studies report improved communication after a speech-generating device (SGD) is included in treatment. Effective interventions that can be modified is necessary to ensure optimal communication outcomes when children do not make anticipated progress. A strength of the study is that these interventions can be adopted by community-based, early service providers. All participants will receive an adapted Stay-Play-Talk (SPT) peer-mediated intervention that varies in active ingredients. With SMART designs, it is possible to test and identify alternative combinations of PMI approaches, such as the addition of a SGD. In this study, 132 preschoolers with ASD (and N=264 peers without disabilities) will be initially randomized to SPT and SGD with spoken peer input only (SPT Basic; peers taught to model language) or SPT and SGD with augmented peer input (SPT Plus; peers taught to use verbal language models concurrently with the SGD). Each child's response to treatment after 5 weeks will determine that child's next phase in the SMART design. Children showing a positive response will continue in their originally assigned group; slow responders will be randomly assigned to receive added treatment components to improve communication (either SPT Plus or SPT Advanced). SPT Advanced adds direct instruction strategies (i.e., adult prompts, reinforcers, and teaching trials) to increase child vocalizations in SGD interventions. The use of a SMART design extends our prior work by testing the systematic addition of selected peer-mediated strategies in combination with an SGD that allows for flexible application of interventions based on child response. The investigators have assembled an outstanding team of highly qualified investigators with complementary skills in preschool assessment, language intervention, clinical trials, and statistics.

Who May Be Eligible (Plain English)

Who May Qualify: - ASD diagnosis - limited or no spoken language defined by less than 20 functional, spontaneous words - currently using or a candidate for a speech-generating device - access to peers without disabilities - English as the primary language spoken at home Who Should NOT Join This Trial: - co-morbid or major medical conditions other than ASD, based on caregiver and teacher report - significant physical, sensory, or motor impairments that would prevent playing with another child - uncorrected visual or hearing impairments that would cause difficulty following peer instructions - a lack of symbol discrimination skills Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * ASD diagnosis * limited or no spoken language defined by less than 20 functional, spontaneous words * currently using or a candidate for a speech-generating device * access to peers without disabilities * English as the primary language spoken at home Exclusion Criteria: * co-morbid or major medical conditions other than ASD, based on caregiver and teacher report * significant physical, sensory, or motor impairments that would prevent playing with another child * uncorrected visual or hearing impairments that would cause difficulty following peer instructions * a lack of symbol discrimination skills

Treatments Being Tested

BEHAVIORAL

Stay-Play-Talk Basic

Stay-Play-Talk (SPT) Basic and SGD with augmented peer input in which peers are taught to model verbal responses while simultaneously selecting screen icons with spoken peer input only (i.e., peers taught to model language)

BEHAVIORAL

Stay-Play-Talk Plus

SPT Plus with augmented SGD peer input (i.e., peers taught to use verbal language models concurrently while selecting SGD icons).

BEHAVIORAL

Stay-Play-Talk Advanced

SPT Advanced adds direct instruction strategies for the children with ASD (i.e., adult prompts, reinforcers, and embedded teaching trials) to increase peer-directed communication.

Locations (2)

Juniper Gardens Children's Project
Kansas City, Kansas, United States
University of North Carolina
Chapel Hill, North Carolina, United States